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173064 ced-1

173064

ced-1

Cell death abnormality protein 1

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Cell death abnormality protein 1

研究结论

Date Results Publications
2018-12-22 10:45:00 Phagocytosing muscle cells promote neuronal regeneration and remove neuronal debris through distinct biochemical functions of CED-1. 30451835
2015-01-03 11:27:00 The formation of such halos depends on the integrins PAT-2/PAT-3, UNC-112 and the GEF protein UIG-1, but not on the canonical ced-1/6/7 or ced-2/5/12 signaling modules. 24632947
2012-12-08 10:02:00 CED-7 and TTR-52 may promote the efflux of PS from apoptotic cells through the generation of extracellular phosphatidylserine (PS) vesicles, which lead to exoplasmic leaflet (exPS) expression on phagocytes via TTR-52 and CED-1 to facilitate cell corpse clearance. 22727702
2010-07-26 12:16:00 TTR-52 is therefore the first bridging molecule identified in C. elegans that mediates recognition of apoptotic cells by crosslinking the PtdSer 'eat me' signal with the phagocyte receptor CED-1. 20526330
2010-03-22 11:27:00 study found that the intracellular protein sorting complex, retromer, was required for cell corpse clearance by mediating the recycling of CED-1; retromer probably acted through direct interaction with CED-1 in the cell corpse recognition pathway 20133524

名称对应

Type IDs
Gene
UniProtKB-ID: CED1_CAEEL
UniprotKB: Q9XWD6
UniParc: UPI000007D1BB, UPI0000081F35, UPI0000074F1B, UPI0000DF0452
EMBL: AF332568, BX284601
EnsemblGenome: WBGene00000415
KO: cel:CELE_Y47H9C.4
Nucleutide sequences
EMBL-CDS: CAD27615.1, CAD27614.1, CAA21739.1, AAG60061.1, CAL44979.1
Gene_ORFName: Y47H9C.4
EnsemblGenome_TRS: Y47H9C.4b.1, Y47H9C.4d.1, Y47H9C.4c.1, Y47H9C.4a.1
Protein sequencees
EnsemblGenome_PRO: Y47H9C.4b.1, Y47H9C.4a.1, Y47H9C.4c.1, Y47H9C.4d.1
RefSeq: NP_001021772.1, NP_001370132.1, NP_001076621.1, NP_740922.1
Others
UniRef100: UniRef100_Q9XWD6
UniRef90: UniRef90_Q9XWD6
UniRef50: UniRef50_Q9XWD6
UniGene: Cel.7093

全选

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