| Type | Description |
|---|---|
| Definition | multiple endocrine neoplasia 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:32:00 | Novel Germline c.105_107dupGCT MEN1 Mutation in a Family with Newly Diagnosed Multiple Endocrine Neoplasia Type 1. | 32847108 |
| 2021-04-03 13:31:00 | Two well-differentiated pancreatic neuroendocrine tumor mouse models. | 31160716 |
| 2020-07-11 12:33:00 | Men1 loss significantly accelerates mutant Kras-dependent oncogenesis, inflammation and impairs Tissue Recovery following Acute Pancreatitis. | 32156729 |
| 2020-05-09 10:58:00 | Established an ATII-specific Kras(G12D/+)/Men1(-/-) driven genetically engineered model and show that deficiency of menin results in the accumulation of DNA damage and antagonizes oncogenic Kras-induced senescence and the epithelial-to-mesenchymal transition during lung tumorigenesis. | 32081882 |
| 2019-12-07 10:09:00 | Restoration of p35 expression in the hippocampus and cortex of Men1 conditional knockout mice rescues synaptic and cognitive deficits associated with Men1 deletion. | 30021166 |
| Type | IDs |
|---|---|
| Synonymous | AW045611 |
| Gene |
UniProtKB-ID:
MEN1_MOUSE,
A0A0R4J1I3_MOUSE
UniprotKB:
O88559,
A0A0R4J1I3
UniParc:
UPI000024DC9E,
UPI00005ACDBD,
UPI00000290C5
EMBL:
AF109390,
BC036287,
AF016398,
AF093756,
AC127556,
AF130368,
AK170713,
AF024513,
AF072755,
AB023401,
AF109389,
AK154371,
CH466612
Ensembl:
ENSMUSG00000024947,
ENSMUSG00000106695
KO:
mmu:17283
|
| Nucleutide sequences |
EMBL-CDS:
AAC79938.1,
EDL33234.1,
AAD38333.1,
EDL33236.1,
AAD37498.1,
AAF01352.1,
BAA74964.1,
BAE32542.1,
AAC78843.1,
BAE41971.1,
AAH36287.1,
AAC26001.1,
AAC79939.1
Ensembl_TRS:
ENSMUST00000201284,
ENSMUST00000113504,
ENSMUST00000079327,
ENSMUST00000113500,
ENSMUST00000202062,
ENSMUST00000202424,
ENSMUST00000202550,
ENSMUST00000202978,
ENSMUST00000078137,
ENSMUST00000056391,
ENSMUST00000113502
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000058149,
ENSMUSP00000078306,
ENSMUSP00000144083,
ENSMUSP00000109128,
ENSMUSP00000109132,
ENSMUSP00000077272,
ENSMUSP00000143830,
ENSMUSP00000143849,
ENSMUSP00000144549,
ENSMUSP00000144028,
ENSMUSP00000109130
RefSeq:
NP_032609.1,
NP_001161960.1,
NP_001161962.1,
NP_001161961.1
|
| Others |
UniRef100:
UniRef100_O88559
UniRef90:
UniRef90_O00255
UniRef50:
UniRef50_O00255
UniGene:
Mm.12917
CCDS:
CCDS29502.1,
CCDS50367.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员