| Type | Description |
|---|---|
| Definition | maternal embryonic leucine zipper kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 10:17:00 | MPK38 phosphorylates p21 at Thr55 stimulating its nuclear translocation, which results in greater association of p21 with peroxisome proliferator-activated receptor gamma (PPARgamma), preventing the PPARgamma transactivation required for adipogenesis. | 31097688 |
| 2019-11-09 10:35:00 | These findings suggest that Smad proteins have class-specific impacts on obesity-associated metabolism by differentially regulating MPK38 activity in diet-induced obese mice. | 29700281 |
| 2015-01-17 12:37:00 | MELK promotes cell migration and invasion via the FAK/Paxillin pathway, and plays an important role in the occurrence and development of gastric cancer. | 24885567 |
| 2014-10-25 12:23:00 | Phosphorylation of the activation loop of MPK38 induces its movement resulting in kinase activation. | 24531485 |
| 2013-11-02 11:35:00 | These results indicate that Trx functions as a physiological inhibitor of MPK38, which plays an important role in inducing ASK1-, TGF-beta, and p53-mediated activity | 23747528 |
| Type | IDs |
|---|---|
| Synonymous | AI327312, MPK38, mKIAA0175 |
| Gene |
UniProtKB-ID:
MELK_MOUSE
UniprotKB:
Q61846
UniParc:
UPI00000E6185
EMBL:
AL805952,
AL807399,
AK145316,
AK011932,
X95351,
AK129076,
L76158,
AK164138
Ensembl:
ENSMUSG00000035683
KO:
mmu:17279
|
| Nucleutide sequences |
EMBL-CDS:
BAE26362.1,
AAB72030.1,
BAC97886.1,
BAE37644.1,
BAB27923.1,
CAA64641.1
Ensembl_TRS:
ENSMUST00000045607
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000043806
RefSeq:
XP_006537703.1,
XP_036019676.1,
NP_034920.2
|
| Others |
UniRef100:
UniRef100_Q61846
UniRef90:
UniRef90_Q61846
UniRef50:
UniRef50_Q14680
UniGene:
Mm.268668
CCDS:
CCDS18124.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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