Type | Description |
---|---|
Definition | cytochrome b5 reductase 3 |
Date | Results | Publications |
---|---|---|
2021-01-02 12:52:00 | The CYB5R3(c) (.350C>G) and G6PD A alleles modify severity of anemia in malaria and sickle cell disease. | 32697331 |
2018-11-03 10:28:00 | study indicated that novel homozygous mutation p.Arg192Cys in CYB5R3 gene present in eight cases and the possibility of high prevalence of heterozygous in Indian population causing Type I recessive congenital methemoglobinemia. | 29482478 |
2017-08-12 10:42:00 | Data suggest that cytochrome b5 (CYB5) and cytochrome b5 reductase 3 (CYB5R3) can reduce human cytoglobin (CYGB) and zebrafish cytoglobins at rates up to 250-fold higher than those reported for the known physiological substrates, hemoglobin and myoglobin; the three proteins (CYB5+CYB5R3+CYGB) appear to constitute a metabolon involved in generation of nitric oxide. | 28671819 |
2016-08-13 11:59:00 | CYB5R3 promotes colonization and metastasis formation and is a prognostic marker of disease-free and overall survival in estrogen receptor-negative breast cancer. | 26351264 |
2016-04-09 11:06:00 | Variants in CYB5A and CYB5R3 should be considered in the evaluation of breast cancer risk in African American women. | 25225034 |
Type | IDs |
---|---|
Synonymous | B5R, DIA1 |
Gene |
UniProtKB-ID:
NB5R3_HUMAN
UniprotKB:
P00387
UniParc:
UPI0000167B09,
UPI00019150F6,
UPI0000161AFB
EMBL:
AJ010116,
AJ310900,
BT009821,
M28706,
AJ010117,
M28707,
M28710,
M28708,
AK302204,
AJ310899,
BC004821,
M28711,
M28709,
M28713,
AF061831,
CR456435,
M28705,
AF061830,
AF361370,
AY341030,
AJ010118,
Y09501,
Z93241,
M16461,
M16462
Ensembl:
ENSG00000100243
KO:
hsa:1727
|
Nucleutide sequences |
EMBL-CDS:
CAC84524.1,
CAA70696.1,
AAP88936.1,
CAA09007.1,
AAF06818.1,
CAG30321.1,
CAA09008.1,
AAA52306.1,
AAH04821.1,
CAC84523.1,
AAA52307.1,
AAA59900.1,
BAH13649.1,
AAP88823.1,
AAF06819.1,
CAA09006.1,
AAL87744.1
Ensembl_TRS:
ENST00000407332,
ENST00000402438,
ENST00000407623,
ENST00000352397,
ENST00000361740
|
Protein sequencees |
Ensembl_PRO:
ENSP00000384834,
ENSP00000385679,
ENSP00000354468,
ENSP00000384457,
ENSP00000338461
RefSeq:
NP_001165132.1,
NP_000389.1,
NP_015565.1,
NP_001123291.1,
NP_001165131.1
|
Others |
UniRef100:
UniRef100_P00387
UniRef90:
UniRef90_P00387
UniRef50:
UniRef50_P00387
UniGene:
Hs.561064
CCDS:
CCDS14040.1,
CCDS33658.1,
CCDS54535.1
|
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Refseq |
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