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172626 lin-28

172626

lin-28

Protein lin-28

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Protein lin-28

研究结论

Date Results Publications
2020-07-04 11:28:00 robust progression from L2 to L3 cell fates depends on the combination of two distinct modes of HBL-1 downregulation: decreased synthesis of HBL-1 via let-7-family microRNA activity, and decreased nuclear accumulation of HBL-1 via action of the lin-28-lin-46 pathway 31597658
2020-01-11 10:42:00 Both LIN-28 and LEP-2 associate with lep-5 in vivo, suggesting that lep-5 directly regulates LIN-28 stability and may function as an RNA scaffold. 30956008
2020-01-04 11:00:00 lin-28 coordinates the timing of hypodermal and somatic gonadal programs for hermaphrodite reproductive system morphogenesis 30745431
2017-09-30 11:11:00 show that CED-3 caspase and the E3 ubiquitin ligase UBR-1 form a complex that couples their in vivo activities, allowing for recognition and rapid degradation of LIN-28 and thus facilitating a switch in developmental programs 28602583
2016-08-06 10:15:00 LEP-2 regulates LIN-28 stability to promote the juvenile-to-adult transition in Caenorhabditis elegans 26811380

名称对应

Type IDs
Gene
UniProtKB-ID: LIN28_CAEEL
UniprotKB: P92186
UniParc: UPI000007F4B5, UPI0000077C21
EMBL: U75915, U75912, BX284601
EnsemblGenome: WBGene00003014
KO: cel:CELE_F02E9.2
Nucleutide sequences
EMBL-CDS: AAC47476.1, AAB49759.1, CAB61008.1, CAB61009.1
Gene_ORFName: F02E9.2
EnsemblGenome_TRS: F02E9.2b.1, F02E9.2a.1
Protein sequencees
EnsemblGenome_PRO: F02E9.2a.1, F02E9.2b.1
RefSeq: NP_001021085.1, NP_492281.2
Others
UniRef100: UniRef100_P92186
UniRef90: UniRef90_P92186
UniRef50: UniRef50_P92186
UniGene: Cel.22515

全选

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研究热度

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