| Type | Description |
|---|---|
| Definition | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 10:46:00 | This study reports the crystal structure of the murine CD98hc extracellular domain and a comprehensive comparison with its human ortholog, revealing only one conserved surface patch that is neither shielded by glycosylation nor by the cell membrane with an accessible surface area typical for an antibody epitope. | 30958588 |
| 2019-12-14 12:17:00 | Inhibition of the amino acid transporter CD98/LAT1 abrogated the leucine-driven mTORC1 activation and reduced natural killer cell effector function | 30696773 |
| 2019-09-14 12:43:00 | SLC3A2 dermal fibroblast deletion induced major skin phenotypes resembling premature aging | 29906411 |
| 2018-12-22 10:45:00 | Cell metabolism regulates integrin mechanosensing via an SLC3A2-dependent sphingolipid biosynthesis pathway. | 30451822 |
| 2018-06-23 10:48:00 | Slc3a2 is required for branched-chain amino-acid-dependent maintenance of Treg cells. | 29141216 |
| Type | IDs |
|---|---|
| Synonymous | 4F2, 4F2HC, AI314110, Cd98, Ly-10, Ly-m10, Ly10, Mdu1, Mgp-2hc, NACAE |
| Gene |
UniProtKB-ID:
4F2_MOUSE,
A0A0U1RPK4_MOUSE
UniprotKB:
P10852,
A0A0U1RPK4
UniParc:
UPI0000475557,
UPI000000009F,
UPI000154BDA5
EMBL:
AC025794,
AK161280,
X14309,
BC065173,
CH466612,
AB023408,
AK165417
Ensembl:
ENSMUSG00000010095
KO:
mmu:17254
|
| Nucleutide sequences |
EMBL-CDS:
BAA90555.1,
BAE38172.1,
EDL33352.1,
CAA32490.1,
AAH65173.1,
BAE36291.1
Ensembl_TRS:
ENSMUST00000170157,
ENSMUST00000010239,
ENSMUST00000206598
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000010239,
ENSMUSP00000130194,
ENSMUSP00000146016
RefSeq:
NP_001154885.1,
XP_017173567.1,
XP_006526796.1,
NP_032603.3,
XP_036017348.1
|
| Others |
UniRef100:
UniRef100_P10852
UniRef90:
UniRef90_P10852
UniRef50:
UniRef50_P08195
UniGene:
Mm.4114
CCDS:
CCDS29540.1,
CCDS50381.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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