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17250 Abcc1

17250

Abcc1

ATP-binding cassette, sub-family C (CFTR/MRP), member 1

protein-coding

Mus musculus

基因描述

Type Description
Definition ATP-binding cassette, sub-family C (CFTR/MRP), member 1

研究结论

Date Results Publications
2019-01-05 12:08:00 Infected Mrp1 knockout mice show decreased iNKT cell responses to antigens from Streptococcus pneumoniae and were associated with increased mortality. 30323255
2018-11-24 11:38:00 The authors conclude that MRP1 assists in depression of polymorphonuclear cell migration by effluxing a molecule that inhibits the proinflammatory effects of MRP2 activity. 29976647
2018-01-27 10:40:00 Mrp1 protects cardiac myocytes and fibroblasts against doxorubicin-induced toxicity, potentially by regulating extracellular redox states. 26822305
2017-09-30 13:43:00 Loss of ABCC1 expression is associated with neonatal hyperbilirubinemia. 28025333
2017-01-28 10:32:00 Data, including data from studies in knockout mice, suggest that Mrp1 is involved in development of vascular endothelial dysfunction in diabetic angiopathy; Mrp1 appears to be required for oxidative stress in endothelial cells due to hyperglycemia. 26908299

名称对应

Type IDs
Synonymous Abcc1a, Abcc1b, MRP, Mdrap, Mrp1
Gene
UniProtKB-ID: MRP1_MOUSE, A5D6P3_MOUSE
UniprotKB: O35379, A5D6P3
UniParc: UPI0000029637
EMBL: BC090617, AF022908, AK029876
Ensembl: ENSMUSG00000023088
KO: mmu:17250
Nucleutide sequences
EMBL-CDS: BAC26654.1, AAB80938.1, AAH90617.1
Ensembl_TRS: ENSMUST00000100167
Protein sequencees
Ensembl_PRO: ENSMUSP00000097743
RefSeq: XP_006521902.2, XP_017172377.1, NP_032602.1, XP_036015706.1
Others
UniRef100: UniRef100_O35379
UniRef90: UniRef90_O35379
UniRef50: UniRef50_P33527-3
UniGene: Mm.196634
CCDS: CCDS37264.1

全选

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研究热度

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