| Type | Description |
|---|---|
| Definition | Phorbol ester/diacylglycerol-binding protein unc-13 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 16:25:00 | A Hyperactive Form of unc-13 Enhances Ca(2+) Sensitivity and Release Probability in C. elegans. | 31509756 |
| 2020-04-04 12:00:00 | Here the authors show that the C2A domain of UNC-13L, like the corresponding domain in mammalian Munc13-1, displays two conserved binding modes: forming C2A/C2A homodimers, or forming a heterodimer with the zinc finger domain of UNC-10/RIM (C2A/RIM). | 30802206 |
| 2019-03-02 12:13:00 | cell-nonautonomous contributions of neuronal KGB-1 (and also in muscle) were effective in driving intestinal gene induction, age-dependent regulation of intestinal DAF-16, and stress resistance, and did not require KGB-1 expression in the target tissue. Additional genetic analyses revealed requirement for UNC-13 in mediating neuronal contributions, indicating involvement of neurotransmission. | 30291110 |
| 2017-09-30 12:14:00 | Thus, our study provides novel mechanistic insights into how Munc18/UNC-18 primes synaptic vesicle release and how this protein interacts functionally with Munc13/UNC-13 and Tomosyn/TOM-1. | 28821673 |
| 2017-09-16 11:18:00 | C1-C2B exerts a basal inhibition on Munc13 in the primed state, permitting calcium- and lipid-dependent control of C1-C2B to modulate synaptic strength | 28772122 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
UNC13_CAEEL,
A0A1C3NSN5_CAEEL,
G5EDN9_CAEEL,
A0A1C3NSL4_CAEEL,
A0A1C3NSH2_CAEEL,
A0A1C3NSI0_CAEEL,
A0A1C3NSJ3_CAEEL
UniprotKB:
P27715,
A0A1C3NSN5,
G5EDN9,
A0A1C3NSL4,
A0A1C3NSH2,
A0A1C3NSI0,
A0A1C3NSJ3
UniParc:
UPI00001B245D,
UPI000034E5D2,
UPI0000086601,
UPI0008047A22,
UPI00001B2456,
UPI0001A959BA,
UPI00001B2455,
UPI000034E5D1,
UPI000002B690,
UPI0008047A02,
UPI000000CAF4,
UPI0000137C42
EMBL:
Z79694,
Z92779,
Z73912,
BX284601,
M62830,
U50735
EnsemblGenome:
WBGene00006752
KO:
cel:CELE_ZK524.2
|
| Nucleutide sequences |
EMBL-CDS:
AAA99781.1,
CAD90190.2,
CAD56619.2,
AAA99780.1,
AAA93094.1,
CAA98147.1,
CAE11317.1,
SBV53354.1,
CAZ65548.1,
SBV53356.1,
SBV53355.1,
SBV53353.1,
SBV53357.1
Gene_ORFName:
ZK524.2,
ZK524.2,
CELE_ZK524.2,
ZK524.2,
CELE_ZK524.2,
ZK524.2,
CELE_ZK524.2,
ZK524.2,
CELE_ZK524.2,
CELE_ZK524.2,
ZK524.2,
ZK524.2,
CELE_ZK524.2
EnsemblGenome_TRS:
ZK524.2c.1,
ZK524.2e.1,
ZK524.2a.1,
ZK524.2d.1
|
| Protein sequencees |
EnsemblGenome_PRO:
ZK524.2d.1,
ZK524.2c.1,
ZK524.2a.1,
ZK524.2e.1
RefSeq:
NP_001021874.1,
NP_001021873.1,
NP_001021871.1,
NP_001317865.1,
NP_001367037.1,
NP_001317866.1,
NP_001317867.1,
NP_001317863.1,
NP_001317864.1,
NP_001293153.1,
NP_001250502.1
|
| Others |
UniRef100:
UniRef100_P27715,
UniRef100_G5EDN9,
UniRef100_A0A1C3NSJ3,
UniRef100_A0A1C3NSL4,
UniRef100_A0A1C3NSN5
UniRef90:
UniRef90_A0A1C3NSJ3,
UniRef90_P27715
UniRef50:
UniRef50_A0A085LX83,
UniRef50_P27715
UniGene:
Cel.16847
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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Ensembl: {{protein.nucleotideEnsembl}} |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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