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172414 glh-1

172414

glh-1

ATP-dependent RNA helicase glh-1

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition ATP-dependent RNA helicase glh-1

研究结论

Date Results Publications
2017-07-15 10:19:00 we show that removal of either of two critical P-granule components, PGL-1 or GLH-1, is sufficient to cause germ cells to express UNC-119::GFP and MYO-3 and to display RNA accumulation defects similar to those observed after depletion of P granules. Our data identify P granules as critical modulators of the germline transcriptome and guardians of germ cell fate. 28258184
2011-05-21 10:24:00 Data show that GLH-1 and its FG domain are not sufficient to form granules, but require factors like PGL-1 to nucleate the localized concentration of GLH proteins. 21402789
2011-04-02 10:04:00 the GLH-1/DCR-1 complex may function in the transport, deposition, or regulation of maternally-transcribed mRNAs and their associated miRNAs. 21146518
2010-01-21 00:00:00 KGB-1 and CSN-5 regulate GLH-1 levels, with GLH-1 targeted for proteosomal degradation by KGB-1 and stabilized by CSN-5. 17699606

名称对应

Type IDs
Gene
UniProtKB-ID: GLH1_CAEEL
UniprotKB: P34689
UniParc: UPI000000C96B
EMBL: FO080897, L19948, U62772
EnsemblGenome: WBGene00001598
KO: cel:CELE_T21G5.3
Nucleutide sequences
EMBL-CDS: AAC27384.1, CCD67591.1, AAB04136.1
Gene_ORFName: T21G5.3
EnsemblGenome_TRS: T21G5.3.1
Protein sequencees
EnsemblGenome_PRO: T21G5.3.1
RefSeq: NP_491963.1
Others
UniRef100: UniRef100_P34689
UniRef90: UniRef90_P34689
UniRef50: UniRef50_P34689
UniGene: Cel.19653

全选

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研究热度

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