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172399 cye-1

172399

cye-1

G1/S-specific cyclin-E

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition G1/S-specific cyclin-E

研究结论

Date Results Publications
2011-07-23 11:08:00 CYE-1/CDK-2 emerges as a critical regulator of stem cell maintenance. We suggest that cyclin E and Cdk-2 may be used broadly to control developmental regulators. 21455289
2011-07-23 11:08:00 Rapid movement through the cell cycle is supported by constitutive CYE-1/CDK-2 activity; CYE-1 and CDK-2 promote the proliferative fate as depletion of cye-1 or cdk-2 in a glp-1 partial loss-of-function mutant causes premature meiotic entry. 21558371
2010-05-03 11:41:00 results suggest that the balance between the levels of CKI and cyclin E determines three distinct cell states: terminally differentiated, quiescent and uncommitted, and proliferating 17476329
2010-01-21 00:00:00 Notch and Prospero repress proliferation following cyclin E overexpression in bristle cell lineage. 19662164
2010-01-21 00:00:00 GLD-1 represses translation of CYE-1/cyclin E during meiotic prophase, which prevents germ cells from re-entering mitosis and inducing embryonic-like transcription 19758560

名称对应

Type IDs
Gene
UniProtKB-ID: CCNE_CAEEL
UniprotKB: O01501
UniParc: UPI000005D643, UPI000018F2FA
EMBL: FO080805, AF520616, AF058331
EnsemblGenome: WBGene00000871
KO: cel:CELE_C37A2.4
Nucleutide sequences
EMBL-CDS: AAM78547.1, CCD66921.1, CCD66922.1, AAC63505.1
Gene_ORFName: C37A2.4
EnsemblGenome_TRS: C37A2.4b.1, C37A2.4a.1
Protein sequencees
EnsemblGenome_PRO: C37A2.4b.1, C37A2.4a.1
RefSeq: NP_001021027.1, NP_001021028.1
Others
UniRef100: UniRef100_O01501
UniRef90: UniRef90_O01501
UniRef50: UniRef50_O01501
UniGene: Cel.9296

全选

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研究热度

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