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172338 gld-2

172338

gld-2

Poly(A) RNA polymerase gld-2

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Poly(A) RNA polymerase gld-2

研究结论

Date Results Publications
2020-10-24 14:10:00 Structures of mammalian GLD-2 proteins reveal molecular basis of their functional diversity in mRNA and microRNA processing. 32633758
2017-09-23 11:01:00 investigate whether the functions of the cytoplasmic poly(A) polymerase (cytoPAP) GLD-2 in C. elegans germ cells exclusively depend on its catalytic activity; findings highlight the enzymatic importance of noncanonical poly(A) polymerases and emphasize the pivotal role of poly(A) tail-centered cytoplasmic mRNA regulation in germ cell biology. 28490506
2015-10-31 11:04:00 GLD-2 thus appears to have evolved specialized nucleotidyl-transferase properties that match the 3' end features of dormant cytoplasmic mRNAs 26124149
2015-01-17 11:53:00 The analyses suggest that GLD-2 activity mediates mRNA stability of many translationally repressed mRNAs. 25217583
2011-12-17 11:40:00 Data suggest that the FBF-2/GLD-2 protein directed polyadenylation of the endogenous mRNA, compensating for that mRNA's natural deadenylation. 21911377

名称对应

Type IDs
Gene
UniProtKB-ID: GLD2_CAEEL, A0A0K3AWQ7_CAEEL, A0A0K3ARE1_CAEEL
UniprotKB: O17087, A0A0K3AWQ7, A0A0K3ARE1
UniParc: UPI0000083E0B, UPI0005303F36, UPI0000002DC1, UPI0000002DC2, UPI0000002DC3, UPI0005303F31
EMBL: BX284601, AY125085, FO081588
EnsemblGenome: WBGene00001596
KO: cel:CELE_ZC308.1
Nucleutide sequences
EMBL-CDS: AAM94369.1, CCD72659.1, CCD72660.1, CCD72661.1, CCD72658.1, CTQ86416.1, CTQ86417.1
Gene_ORFName: ZC308.1, ZC308.1, CELE_ZC308.1, ZC308.1, CELE_ZC308.1
EnsemblGenome_TRS: ZC308.1a.1, ZC308.1c.1, ZC308.1b.1, ZC308.1d.1
Protein sequencees
EnsemblGenome_PRO: ZC308.1d.1, ZC308.1b.1, ZC308.1a.1, ZC308.1c.1
RefSeq: NP_001021844.1, NP_491841.2, NP_001300478.1, NP_491842.2, NP_001300477.1
Others
UniRef100: UniRef100_O17087
UniRef90: UniRef90_O17087
UniRef50: UniRef50_O17087
UniGene: Cel.9280

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