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17227 Mcpt4

17227

Mcpt4

mast cell protease 4

protein-coding

Mus musculus

基因描述

Type Description
Definition mast cell protease 4

研究结论

Date Results Publications
2020-02-08 12:17:00 Data indicate a role of mouse mast cell protease-4 (mMCP4) in post-myocardial infarction (MI) dysfunction by regulating myocardial protease expression and cardiomyocyte death without significant impact on myocardial fibrosis or survival post-MI in mice. 30639224
2020-01-04 12:40:00 mMCP-4 activity is enhanced both centrally and systemically in a mouse model of EAE 31248979
2019-08-03 12:18:00 we demonstrate that MCTP4 is critical to prevent Group B Streptococcus infection-associated disease severity 28916188
2017-07-15 10:07:00 deletion of the gene encoding MMCP-4 (Mcpt4), markedly reduced late, but not early, infarct size by suppressing IGF-1 degradation and, consequently, diminished cardiac dysfunction and adverse structural remodeling 27274047
2017-05-20 13:58:00 study supports a role for mMCP-4 in the early inflammatory phases of the disease in a mouse model of MS. 27610007

名称对应

Type IDs
Synonymous MMCP-4, MMCP-4A, MMCP-4B, Mcp-4, Mcp4
Gene
UniProtKB-ID: MCPT4_MOUSE, Q3UN88_MOUSE
UniprotKB: P21812, Q3UN88
UniParc: UPI0000029445, UPI00000213D9
EMBL: AC163646, AK144385, AY007569, M55616, X68804, M55617, AB051900
Ensembl: ENSMUSG00000061068
KO: mmu:17227
Nucleutide sequences
EMBL-CDS: CAA48704.1, BAB18732.1, AAG24503.1, AAA39989.1, AAA72939.1, BAE25859.1
Ensembl_TRS: ENSMUST00000043249
Protein sequencees
Ensembl_PRO: ENSMUSP00000038103
RefSeq: NP_034909.2
Others
UniRef100: UniRef100_P21812, UniRef100_Q3UN88
UniRef90: UniRef90_P21812, UniRef90_Q3UN88
UniRef50: UniRef50_P23946, UniRef50_P00770
UniGene: Mm.439684
CCDS: CCDS27140.1

全选

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