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172209 tom-1

172209

tom-1

TOMosyn synaptic protein

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition TOMosyn synaptic protein

研究结论

Date Results Publications
2017-09-30 12:14:00 Thus, our study provides novel mechanistic insights into how Munc18/UNC-18 primes synaptic vesicle release and how this protein interacts functionally with Munc13/UNC-13 and Tomosyn/TOM-1. 28821673
2010-01-21 00:00:00 tomosyn negatively regulates transmitter and neuropeptide release in vesicle exocytosis 17627987
2010-01-21 00:00:00 These data indicate that in the intact nervous system, TOM-1 negatively regulates synaptic vesicle priming. 16895441
2010-01-21 00:00:00 Synaptic vesicle priming is modulated by the balance between Tomosyn and UNC-13, perhaps by regulating the availability of open-syntaxin. 16880125
2010-01-21 00:00:00 Overexpression of tomosyn leads to an accumulation of dense-core vesicles at the presynapse. 17881523

名称对应

Type IDs
Gene
UniProtKB-ID: Q49HI3_CAEEL, G5EE26_CAEEL, Q14DX2_CAEEL, A8WFN4_CAEEL, A0A0K3ATN9_CAEEL, A0A0K3AR90_CAEEL, A0A0K3AWL6_CAEEL
UniprotKB: Q49HI3, G5EE26, Q14DX2, A8WFN4, A0A0K3ATN9, A0A0K3AR90, A0A0K3AWL6
UniParc: UPI000057C563, UPI0000DA6B78, UPI0005CDCF9E, UPI0005303EDD, UPI00015E5052, UPI0000DA6B77, UPI0005303EA6
EMBL: AY912102, AY997305, AY997306, BX284601
EnsemblGenome: WBGene00006594
KO: cel:CELE_M01A10.2
Nucleutide sequences
EMBL-CDS: AAX89145.1, CCD72080.1, AAY44303.1, CCD72085.1, CCD72084.1, AAY44302.1, CCD72086.1, CTQ86368.1, CTQ86367.1, CTQ86366.1
Gene_ORFName: CELE_M01A10.2, M01A10.2, M01A10.2, CELE_M01A10.2, CELE_M01A10.2, M01A10.2, CELE_M01A10.2, M01A10.2, M01A10.2, CELE_M01A10.2, M01A10.2, CELE_M01A10.2, M01A10.2, CELE_M01A10.2
Protein sequencees
RefSeq: NP_001300428.1, NP_001122494.1, NP_001300429.1, NP_491623.3, NP_001300427.1, NP_491626.2, NP_001122495.1
Others
UniRef100: UniRef100_Q14DX2, UniRef100_A0A0K3AWL6, UniRef100_G5EE26, UniRef100_Q49HI3, UniRef100_A0A0K3AR90, UniRef100_A0A0K3ATN9, UniRef100_A8WFN4
UniRef90: UniRef90_A8WFN4, UniRef90_A0A0K3ATN9
UniRef50: UniRef50_A0A0K3ATN9, UniRef50_A8WFN4
UniGene: Cel.5999

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