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172174 erm-1

172174

erm-1

Ezrin/Radixin/Moesin

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Ezrin/Radixin/Moesin

研究结论

Date Results Publications
2021-03-27 14:43:00 C-terminal phosphorylation modulates ERM-1 localization and dynamics to control cortical actin organization and support lumen formation during Caenorhabditis elegans development. 32586975
2019-01-12 11:38:00 We evidence that wild-type ezrin (ezrinWT) and its phosphomimetic mutant T567D (ezrinTD) do not deform membranes but self-assemble anti-parallelly, zipping adjacent membranes. EzrinTD's specific conformation reduces intermolecular interactions, allows binding to actin filaments, which reduces membrane tethering, and promotes ezrin binding to positively-curved membranes. 30234483
2016-01-02 11:41:00 fortifying the link between the apical membrane and actin cortex by overexpression of the ezrin/radixin/moesin ortholog ERM-1, significantly rescued cyst formation and ruptures in the pigv-1(qm34) mutant. 25807459
2014-11-29 10:04:00 ERM-1 prevents the immediate activation of the entire pool of LET-23 EGFR and permits the generation of a long-lasting inductive signal 24785082
2013-03-30 11:21:00 Propose that the ERM-1/AQP-8 interaction propels lumen extension by translumenal flux, suggesting a direct morphogenetic effect of water-channel-regulated fluid pressure. 23334498

名称对应

Type IDs
Gene
UniProtKB-ID: G5EES2_CAEEL, G5EBK3_CAEEL
UniprotKB: G5EES2, G5EBK3
UniParc: UPI000007CD6E, UPI0000075DAD
EMBL: AB107270, AY643538, AB107268, BX284601, AB107269
EnsemblGenome: WBGene00001333
KO: cel:CELE_C01G8.5
Nucleutide sequences
EMBL-CDS: BAC98354.1, CCD62462.1, BAC98356.1, AAT66914.1, CCD62463.1, BAC98355.1, BAC98358.1
Gene_ORFName: CELE_C01G8.5, C01G8.5, C01G8.5, CELE_C01G8.5
Protein sequencees
RefSeq: NP_491560.1, NP_491559.1
Others
UniRef100: UniRef100_G5EES2, UniRef100_G5EBK3
UniRef90: UniRef90_G5EBK3
UniRef50: UniRef50_G5EBK3
UniGene: Cel.5070

全选

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