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17216 Mcm2

17216

Mcm2

minichromosome maintenance complex component 2

protein-coding

Mus musculus

基因描述

Type Description
Definition minichromosome maintenance complex component 2

研究结论

Date Results Publications
2018-11-03 12:04:00 Segregation of parental histones to the leading strand increased markedly in cells with histone-binding mutations in MCM2, part of the replicative helicase, exacerbating histone posttranslational modifications sister chromatid asymmetry. 30115746
2017-07-01 10:17:00 MCM2 is dynamically expressed in both proliferative and differentiated stromal cells during mouse periimplantation uterus. expression of Mcm2 is induced by progesterone action in the mouse uterine stroma. siRNA-mediated silencing of MCM2 arrests the cell cycle at G1-S transition during stromal cell proliferation. downregulation of Mcm2 could also compromise stromal cell differentiation. 26910396
2016-05-21 12:07:00 MCM2 deficiency reduces DNA replication initiation in gene-rich regions of the genome. 25762552
2016-05-14 11:49:00 these data demonstrate that active MCM2-7 repression is a physiologically important mechanism for RS-induced cell cycle arrest and genome maintenance on an organismal level. 26765334
2012-12-08 10:59:00 Hematopoietic cells originally express higher levels MCM 2 protein and undergo more frequent apoptosis following doxorubicin-induced DNA-damage in the presence of the FLV envelope protein gp70. 22768239

名称对应

Type IDs
Synonymous AA959861, AW476101, BM28, CDCL1, Mcmd2, mKIAA0030
Gene
UniProtKB-ID: MCM2_MOUSE
UniprotKB: P97310
UniParc: UPI00000EA00F
EMBL: BC055318, U89403, AK129039, D86725, AF004105, AK088156
Ensembl: ENSMUSG00000002870
KO: mmu:17216
Nucleutide sequences
EMBL-CDS: AAH55318.1, AAC16250.1, BAA22148.1, AAC36510.1, BAC97849.1, BAC40178.1
Ensembl_TRS: ENSMUST00000058011
Protein sequencees
Ensembl_PRO: ENSMUSP00000061923
RefSeq: NP_032590.2
Others
UniRef100: UniRef100_P97310
UniRef90: UniRef90_P97310
UniRef50: UniRef50_P49736
UniGene: Mm.16711
CCDS: CCDS39554.1

全选

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研究热度

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