Type | Description |
---|---|
Definition | minichromosome maintenance complex component 2 |
Date | Results | Publications |
---|---|---|
2018-11-03 12:04:00 | Segregation of parental histones to the leading strand increased markedly in cells with histone-binding mutations in MCM2, part of the replicative helicase, exacerbating histone posttranslational modifications sister chromatid asymmetry. | 30115746 |
2017-07-01 10:17:00 | MCM2 is dynamically expressed in both proliferative and differentiated stromal cells during mouse periimplantation uterus. expression of Mcm2 is induced by progesterone action in the mouse uterine stroma. siRNA-mediated silencing of MCM2 arrests the cell cycle at G1-S transition during stromal cell proliferation. downregulation of Mcm2 could also compromise stromal cell differentiation. | 26910396 |
2016-05-21 12:07:00 | MCM2 deficiency reduces DNA replication initiation in gene-rich regions of the genome. | 25762552 |
2016-05-14 11:49:00 | these data demonstrate that active MCM2-7 repression is a physiologically important mechanism for RS-induced cell cycle arrest and genome maintenance on an organismal level. | 26765334 |
2012-12-08 10:59:00 | Hematopoietic cells originally express higher levels MCM 2 protein and undergo more frequent apoptosis following doxorubicin-induced DNA-damage in the presence of the FLV envelope protein gp70. | 22768239 |
Type | IDs |
---|---|
Synonymous | AA959861, AW476101, BM28, CDCL1, Mcmd2, mKIAA0030 |
Gene |
UniProtKB-ID:
MCM2_MOUSE
UniprotKB:
P97310
UniParc:
UPI00000EA00F
EMBL:
BC055318,
U89403,
AK129039,
D86725,
AF004105,
AK088156
Ensembl:
ENSMUSG00000002870
KO:
mmu:17216
|
Nucleutide sequences |
EMBL-CDS:
AAH55318.1,
AAC16250.1,
BAA22148.1,
AAC36510.1,
BAC97849.1,
BAC40178.1
Ensembl_TRS:
ENSMUST00000058011
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000061923
RefSeq:
NP_032590.2
|
Others |
UniRef100:
UniRef100_P97310
UniRef90:
UniRef90_P97310
UniRef50:
UniRef50_P49736
UniGene:
Mm.16711
CCDS:
CCDS39554.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员