| Type | Description |
|---|---|
| Definition | minichromosome maintenance complex component 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-02 11:32:00 | Study characterize the interaction of Keap1, a central antioxidant response regulator in Metazoa, with the replicative helicase subunit protein MCM3. Analysis suggests that structural determinants of the interaction of Keap1 with its critical downstream target - Nrf2 master transactivator of oxidative stress response genes - may have evolved in evolution to mimic the conserved helix-2-insert motif of MCM3. | 30108253 |
| 2016-05-21 13:03:00 | Mcm3-deficient erythroblasts display aberrant DNA replication patterns and fail to complete maturation, causing lethal anemia. | 26456157 |
| 2010-01-21 00:00:00 | These data reveal that CDK-dependent MCM3 phosphorylation contributes to the regulated formation of the MCM2-7 complex. | 18524952 |
| 2010-01-21 00:00:00 | Depletion of Orc2 and Mcm3 by siRNA leads to an inhibition of cell proliferation, an altered cell cycle distribution as well as to multinucleated cells with insufficiently organised microtubules. | 17157410 |
| 2010-01-21 00:00:00 | analysis of carboxyl-terminal MCM3 phosphorylation sites and their motifs | 17244605 |
| Type | IDs |
|---|---|
| Synonymous | AL033361, C80350, Mcmd, P1, P1-MCM3, p1.m |
| Gene |
UniProtKB-ID:
MCM3_MOUSE,
Q3UI57_MOUSE
UniprotKB:
P25206,
Q3UI57
UniParc:
UPI0000001A8E
EMBL:
AK147065,
X62154,
AK148006,
BC031700,
AK146497,
D26088
Ensembl:
ENSMUSG00000041859
KO:
mmu:17215
|
| Nucleutide sequences |
EMBL-CDS:
AAH31700.1,
CAA44079.1,
BAA05081.1,
BAE28283.1,
BAE27213.1,
BAE27649.1
Ensembl_TRS:
ENSMUST00000053266
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000059192
RefSeq:
NP_032589.1,
XP_030107786.1
|
| Others |
UniRef100:
UniRef100_P25206
UniRef90:
UniRef90_P25205
UniRef50:
UniRef50_P25205
UniGene:
Mm.4502
CCDS:
CCDS14843.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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