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172041 dhc-1

172041

dhc-1

Dynein heavy chain, cytoplasmic

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Dynein heavy chain, cytoplasmic

研究结论

Date Results Publications
2020-06-27 12:09:00 The polarity-induced force imbalance in Caenorhabditis elegans embryos is caused by asymmetric binding rates of dynein to the cortex. 30332325
2018-12-01 12:11:00 Data indicate a role for DHC-1, the dynein heavy chain, in maintaining neuronal cargo distribution. 28406181
2017-10-07 13:02:00 Dynein tethered to the cell cortex generates pulling forces that position the mitotic spindle. Two distinct cortical dynein populations together create a robust force-generating system in the polarized one-cell Caenorhabditis elegans embryo. 28739679
2017-08-26 11:09:00 we dissect the role of dynactin's microtubule binding activity, located in the p150 CAP-Gly domain and an adjacent basic patch, in the C. elegans zygote. Our results suggest that p150 GAP-Gly domain binding to microtubules promotes initiation of dynein-mediated organelle transport in the dividing one-cell embryo, and that this function of p150 is critical for generating cytoplasmic pulling forces for centrosome 28759579
2015-09-05 11:04:00 Mutations affecting dhc-1 and cyb-3 cooperate to increase fitness in the absence of MDF-1. 25486568

名称对应

Type IDs
Gene
UniProtKB-ID: DYHC_CAEEL, A0A163VTS9_CAEEL
UniprotKB: Q19020, A0A163VTS9
UniParc: UPI0007BCFBC0, UPI000013C4A3
EMBL: BX284601, L33260
EnsemblGenome: WBGene00000962
KO: cel:CELE_T21E12.4
Nucleutide sequences
EMBL-CDS: AAC37251.1, CCD64267.1, SAP35528.1
Gene_ORFName: T21E12.4, T21E12.4, CELE_T21E12.4
EnsemblGenome_TRS: T21E12.4a.2, T21E12.4a.1
Protein sequencees
EnsemblGenome_PRO: T21E12.4a.2, T21E12.4a.1
RefSeq: NP_491363.1, NP_001317773.1
Others
UniRef100: UniRef100_Q19020
UniRef90: UniRef90_Q19020
UniRef50: UniRef50_Q19020
UniGene: Cel.19011

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