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17202 Mc4r

17202

Mc4r

melanocortin 4 receptor

protein-coding

Mus musculus

基因描述

Type Description
Definition melanocortin 4 receptor

研究结论

Date Results Publications
2021-01-09 13:29:00 Signal pathway analysis of selected obesity-associated melanocortin-4 receptor class V mutants. 32423884
2020-07-04 10:28:00 Late onset obesity in mice with targeted deletion of potassium inward rectifier Kir7.1 from cells expressing the melanocortin-4 receptor. 30561082
2020-02-08 12:15:00 The melanocortin system, through MC4R, is involved in amylin-induced suppression of food intake and activation of thermogenesis in both the hypothalamus and interscapular brown adipose tissue via modulation of Acetyl-coA carboxylase phosphorylation and UCP1 expression. 30851142
2020-01-18 13:01:00 These results indicate that melanocortin signaling via the MC4R on oxytocin neurons is important for normal ejaculation independent of the male's metabolic health. 30756300
2019-09-21 11:25:00 investigated the role of melanocortin 4 receptors (MC4Rs) in aversive processing using genetically modified mice and a behavioral test in which mice avoid an environment that they have learned to associate with aversive stimuli 29911992

名称对应

Type IDs
Synonymous Mc4-r, Pkcp
Gene
UniProtKB-ID: MC4R_MOUSE
UniprotKB: P56450
UniParc: UPI0000195724
EMBL: AY684818, AY684820, AY684814, AY684819, AF201662, BC116957, BC116959, AY684813, AK136793, AY684815, AB009664
Ensembl: ENSMUSG00000047259
KO: mmu:17202
Nucleutide sequences
EMBL-CDS: AAV92656.1, AAV92655.1, AAV92649.1, AAV92654.1, AAV92651.1, BAE23130.1, AAI16958.1, AAI16960.1, AAG35602.1, AAV92650.1, BAA24015.1
Ensembl_TRS: ENSMUST00000057942
Protein sequencees
Ensembl_PRO: ENSMUSP00000054776
RefSeq: NP_058673.2
Others
UniRef100: UniRef100_P56450
UniRef90: UniRef90_P32245
UniRef50: UniRef50_P32245
UniGene: Mm.229447, Mm.491749
CCDS: CCDS29316.1

全选

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