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17201 Mc3r

17201

Mc3r

melanocortin 3 receptor

protein-coding

Mus musculus

基因描述

Type Description
Definition melanocortin 3 receptor

研究结论

Date Results Publications
2019-12-07 10:31:00 Mc3R neurons lie within lateral hypothalamic area neurocircuitry that modulates locomotor activity and energy expenditure and contribute to energy balance control. 30541071
2019-09-14 10:21:00 important in response of arcuate nucleus neurons to fasting 30307151
2018-11-10 10:42:00 MC3Rs expressed in Nkx2.1(+ve) neurons are sufficient to coordinate hypothalamic response and expression of compulsive behavioral responses involving meal anticipation and consumption of large meals during situations of prolonged negative energy balance. 28294152
2016-06-11 11:56:00 Replacing murine Mc3r with and double-mutant (C17A+G241A) human MC3R showed greater weight and fat mass, increased energy intake and feeding efficiency. 26818770
2015-11-21 11:55:00 MC1-mediated effects were reduced, and MC3 anti-inflammatory circuits predominated. Mice bearing a nonfunctional MC1 displayed a transient exacerbation of neutrophil recruitment after global I/R, which diminished by 2 hours. 26112010

名称对应

Type IDs
Synonymous MC3-R
Gene
UniProtKB-ID: MC3R_MOUSE, Q544G7_MOUSE
UniprotKB: P33033, Q544G7
UniParc: UPI0000004010
EMBL: X74983, AK038677, BC104730, BC105667, BC105668
Ensembl: ENSMUSG00000038537
KO: mmu:17201
Nucleutide sequences
EMBL-CDS: CAA52918.1, AAI05668.1, BAC30094.1, AAI05669.1, AAI04731.1
Ensembl_TRS: ENSMUST00000038532
Protein sequencees
Ensembl_PRO: ENSMUSP00000047358
RefSeq: NP_032587.1
Others
UniRef100: UniRef100_P33033
UniRef90: UniRef90_P33033
UniRef50: UniRef50_P33033
UniGene: Mm.57183
CCDS: CCDS17127.1

全选

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研究热度

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