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171990 unc-89

171990

unc-89

Muscle M-line assembly protein unc-89

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Muscle M-line assembly protein unc-89

研究结论

Date Results Publications
2021-02-02 13:26:00 A Region of UNC-89 (Obscurin) Lying between Two Domains Is a Highly Elastic Spring Required for Proper Sarcomere Organization. 32645312
2012-12-22 10:44:00 study demonstrates that the level of MEI-1 protein is reduced in an unc-89 mutant, indicating that the normal role of UNC-89 is to inhibit the CUL-3/MEL-26 complex toward MEI-1 in striated muscle 22621901
2012-11-17 10:24:00 data implicates UNC-89 in maintaining muscle cell architecture and that this precise organization is essential for optimal calcium mobilization and efficient and effective muscle contraction. 22768340
2010-01-21 00:00:00 Results support a model in which the DH-PH region of UNC-89 activates RHO-1 GTPase for organization of myosin filaments in C. elegans muscle cells. 18801371
2010-01-21 00:00:00 Results show that the coding sequence for unc-89 is larger than originally thought, and that the gene encodes at least four major isoforms. 15313609

名称对应

Type IDs
Gene
UniProtKB-ID: UNC89_CAEEL
UniprotKB: O01761
UniParc: UPI00001A98EA, UPI000045239B, UPI00001101B7, UPI000045239D, UPI00001A97AD, UPI0000452233, UPI000045239C
EMBL: FO080458, U33058, AY724774, AY714779
EnsemblGenome: WBGene00006820
KO: cel:CELE_C09D1.1
Nucleutide sequences
EMBL-CDS: CCD63869.1, CCD63864.1, CCD63868.1, CCD63866.1, CCD63870.1, AAU21474.1, AAB00542.1, CCD63865.1, AAU14146.1, CCD63867.1
Gene_ORFName: C09D1.1
EnsemblGenome_TRS: C09D1.1d.1, C09D1.1e.1, C09D1.1g.1, C09D1.1c.1, C09D1.1a.1, C09D1.1b.1, C09D1.1f.1
Protein sequencees
EnsemblGenome_PRO: C09D1.1c.1, C09D1.1g.1, C09D1.1e.1, C09D1.1d.1, C09D1.1f.1, C09D1.1a.1, C09D1.1b.1
RefSeq: NP_001020985.1, NP_001343711.1, NP_001020984.1, NP_001343714.1, NP_001020989.1, NP_001343716.1, NP_001343717.1, NP_001020988.1, NP_001343713.1, NP_001293453.1, NP_001343617.1, NP_001293454.1, NP_001343718.1, NP_001343712.1, NP_001343719.1, NP_001343715.1
Others
UniRef100: UniRef100_O01761
UniRef90: UniRef90_O01761
UniRef50: UniRef50_O01761
UniGene: Cel.7125

全选

研究热度
发表文献
研究结论
热点单位
排名 科研单位 文献
1

Emory University

9
2

University of Toronto

2
3

Boston University

1
4

Central China Normal University

1
5

Swiss Institute for Bioinformatics

1
热点人员
排名 研究人员 文献
1

Guy M Benian

11
2

Hiroshi Qadota

8
3

Ge Xiong

3
4

Kristina B Mercer

3
5

Kristy J Wilson

3
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