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171988 unc-73

171988

unc-73

hypothetical protein

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition hypothetical protein

研究结论

Date Results Publications
2016-02-20 11:44:00 UNC-73, the C. elegans ortholog of Trio, is a guanine nucleotide exchange factor (GEF) upstream of both CED-10 and MIG-2 that is suppressed by CMRL1 26395474
2012-05-12 11:12:00 we propose a bipartite model for UNC-73/TRIO activity in excretory canal extension. 21996675
2012-01-21 10:55:00 UNC-73 RhoGEF-2 isoforms are required for proper neurotransmitter signaling and may function in the DCV-mediated neuromodulatory regulation of locomotion rate. 21750262
2010-01-21 00:00:00 Mutants with impaired growth cone functions, such as unc-73C, often exhibit abnormal terminations and inappropriate trajectories at the distal ends of the M2 axons. 12885562
2010-01-21 00:00:00 Trio's Rho-specific GEF domain (unc-73)is a major Galpha(q) effector that, together with PLCbeta, mediates the Galpha(q) signaling that drives the locomotion, egg laying, and growth. 17942708

名称对应

Type IDs
Gene
UniProtKB-ID: O61528_CAEEL, Q7KPP4_CAEEL, H2KYM4_CAEEL, Q7JNG6_CAEEL, Q7JNG4_CAEEL, H2KYM2_CAEEL, Q95Q51_CAEEL
UniprotKB: O61528, Q7KPP4, H2KYM4, Q7JNG6, Q7JNG4, H2KYM2, Q95Q51
UniParc: UPI0001923818, UPI000002A21E, UPI0001923817, UPI000002A21C, UPI000000CAAD, UPI00000611F8, UPI000002A21D
EMBL: AF048834, AF048835, BX284601
EnsemblGenome: WBGene00006805
KO: cel:CELE_F55C7.7
Nucleutide sequences
EMBL-CDS: CCD63876.1, AAC12931.1, AAC12932.1, CCD63877.1, CCD63883.1, CCD63878.1, CCD63879.1, CCD63881.1, CCD63880.1
Gene_ORFName: F55C7.7, CELE_F55C7.7, F55C7.7, CELE_F55C7.7, CELE_F55C7.7, F55C7.7, CELE_F55C7.7, F55C7.7, CELE_F55C7.7, F55C7.7, CELE_F55C7.7, F55C7.7, CELE_F55C7.7, F55C7.7
Protein sequencees
RefSeq: NP_001367474.1, NP_001021500.1, NP_001249513.1, NP_001021499.1, NP_001361940.1, NP_001249512.1, NP_001021496.1, NP_001021497.1, NP_001021498.1
Others
UniRef100: UniRef100_Q7JNG4, UniRef100_Q7JNG6, UniRef100_Q7KPP4, UniRef100_H2KYM2, UniRef100_Q95Q51, UniRef100_H2KYM4, UniRef100_O61528
UniRef90: UniRef90_Q95Q51, UniRef90_Q7JNG4, UniRef90_Q7JNG6, UniRef90_Q7KPP4, UniRef90_O61528
UniRef50: UniRef50_Q95Q51, UniRef50_O61528, UniRef50_Q7JNG6, UniRef50_Q7KPP4
UniGene: Cel.22600

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研究热度

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