mek-2 - Dual specificity mitogen-activated protein kinase kinase mek-2-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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171872 mek-2

基因描述

Type	Description
Definition	Dual specificity mitogen-activated protein kinase kinase mek-2

研究结论

Date	Results	Publications
2011-04-23 11:27:00	C. elegans ERK kinase MPK-1 or ERK phosphorylating/activating kinase MEK-2 constitutively activates native ClC anion channel CLH-3b upstream from Gck-3.	21160027

名称对应

Type	IDs
Gene	UniProtKB-ID: MEK2_CAEEL UniprotKB: Q10664 UniParc: UPI000012EEC6 EMBL: U21107, FO081804 EnsemblGenome: WBGene00003186 KO: cel:CELE_Y54E10BL.6
Nucleutide sequences	EMBL-CDS: AAA85118.1, CCD73487.1 Gene_ORFName: Y54E10BL.6 EnsemblGenome_TRS: Y54E10BL.6.1
Protein sequencees	EnsemblGenome_PRO: Y54E10BL.6.1 RefSeq: NP_491087.1
Others	UniRef100: UniRef100_Q10664 UniRef90: UniRef90_Q10664 UniRef50: UniRef50_Q10664 UniGene: Cel.19739

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
31308550	EPIC: software toolkit for elution profile-based inference of protein complexes. Nat Methods Lucas ZhongMing Hu , Florian Goebels , June H Tan , Eric Wolf , Uros Kuzmanov , Cuihong Wan , Sadhna Phanse , Changjiang Xu , Mike Schertzberg , Andrew G Fraser , Gary D Bader , Andrew Emili	2019-08-01	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21160027	C. elegans STK39/SPAK ortholog-mediated inhibition of ClC anion channel activity is regulated by WNK-independent ERK kinase signaling. Am J Physiol Cell Physiol Rebecca A Falin , Hiroaki Miyazaki , Kevin Strange	2011-03-01	-
18692475	A protein domain-based interactome network for C. elegans early embryogenesis. Cell Mike Boxem , Zoltan Maliga , Niels Klitgord , Na Li , Irma Lemmens , Miyeko Mana , Lorenzo de Lichtervelde , Joram D Mul , Diederik van de Peut , Maxime Devos , Nicolas Simonis , Muhammed A Yildirim , Murat Cokol , Huey-Ling Kao , Anne-Sophie de Smet , Haidong Wang , Anne-Lore Schlaitz , Tong Hao , Stuart Milstein , Changyu Fan , Mike Tipsword , Kevin Drew , Matilde Galli , Kahn Rhrissorrakrai , David Drechsel , Daphne Koller , Frederick P Roth , Lilia M Iakoucheva , A Keith Dunker , Richard Bonneau , Kristin C Gunsalus , David E Hill , Fabio Piano , Jan Tavernier , Sander van den Heuvel , Anthony A Hyman , Marc Vidal	2008-08-08	-
18073423	Multiple functions and dynamic activation of MPK-1 extracellular signal-regulated kinase signaling in Caenorhabditis elegans germline development. Genetics Min-Ho Lee , Mitsue Ohmachi , Swathi Arur , Sudhir Nayak , Ross Francis , Diane Church , Eric Lambie , Tim Schedl	2007-12-01	-
17417969	Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. BMC Dev. Biol. Julian Ceron , Jean-FranÃ§ois Rual , Abha Chandra , Denis Dupuy , Marc Vidal , Sander van den Heuvel	2007-01-01	T24H7.8, Y48A6C.2, Y48A6C.6, srz-80, B0513.7, C53D5.5, rpl-17, smg-2, spe-15, egl-30, Y23H5B.6, snr-7, pop-1, mek-2, col-48, arx-7, riok-1, cdt-1, W05F2.3, rnp-6, inx-13, C50F2.3, inx-16, cdc-6, anc-1, bet-1, got-2.1, use-1, mat-1, prp-31, tyms-1, spd-5, cir-1, dnj-21, C32F10.4, lin-35, hmg-3, F33D11.10, pigv-1, rps-17, gld-2, san-1, ncbp-1, F57B10.8, dhod-1, cytb-5.2, unc-37, gpc-2, cye-1, teg-4, sacy-1, C48B6.2, sem-4, nuo-6, prpf-4, hlh-2, mlt-2, adsl-1, unc-15, col-35, D2030.4, capg-1, lron-9, gna-2, tag-173, taf-5, rskn-2, cdc-48.3, kin-10, npp-2, F10D11.6, unc-120, cdc-5L, cfim-1, mfap-1, F43G9.12, sig-7, asg-1, pbs-7, dhfr-1, gls-1, lmn-1, snpc-4, C31H5.6, nduf-7, mrpl-54, F25H5.5, skr-2, skr-1, stl-1, klp-16, gfi-2, T23D8.3, his-68, blmp-1, pab-1, rpl-30, sec-8, ndk-1
15268855	The ERK MAP kinase cascade mediates tail swelling and a protective response to rectal infection in C. elegans. Curr. Biol. Hannah R Nicholas , Jonathan Hodgkin	2004-07-27	mek-2, sur-2, mpk-1, lin-45, lin-25, ksr-1
14704431	A map of the interactome network of the metazoan C. elegans. Science Siming Li , Christopher M Armstrong , Nicolas Bertin , Hui Ge , Stuart Milstein , Mike Boxem , Pierre-Olivier Vidalain , Jing-Dong J Han , Alban Chesneau , Tong Hao , Debra S Goldberg , Ning Li , Monica Martinez , Jean-FranÃ§ois Rual , Philippe Lamesch , Lai Xu , Muneesh Tewari , Sharyl L Wong , Lan V Zhang , Gabriel F Berriz , Laurent Jacotot , Philippe Vaglio , JÃ©rÃ´me Reboul , Tomoko Hirozane-Kishikawa , Qianru Li , Harrison W Gabel , Ahmed Elewa , Bridget Baumgartner , Debra J Rose , Haiyuan Yu , Stephanie Bosak , Reynaldo Sequerra , Andrew Fraser , Susan E Mango , William M Saxton , Susan Strome , Sander Van Den Heuvel , Fabio Piano , Jean Vandenhaute , Claude Sardet , Mark Gerstein , Lynn Doucette-Stamm , Kristin C Gunsalus , J Wade Harper , Michael E Cusick , Frederick P Roth , David E Hill , Marc Vidal	2004-01-23	-
12679813	C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Nat. Genet. JÃ©rÃ´me Reboul , Philippe Vaglio , Jean-FranÃ§ois Rual , Philippe Lamesch , Monica Martinez , Christopher M Armstrong , Siming Li , Laurent Jacotot , Nicolas Bertin , Rekin's Janky , Troy Moore , James R Hudson , James L Hartley , Michael A Brasch , Jean Vandenhaute , Simon Boulton , Gregory A Endress , Sarah Jenna , Eric Chevet , Vasilis Papasotiropoulos , Peter P Tolias , Jason Ptacek , Mike Snyder , Raymond Huang , Mark R Chance , Hongmei Lee , Lynn Doucette-Stamm , David E Hill , Marc Vidal	2003-05-01	-
11882296	C. elegans ksr-1 and ksr-2 have both unique and redundant functions and are required for MPK-1 ERK phosphorylation. Curr. Biol. Mitsue Ohmachi , Christian E Rocheleau , Diane Church , Eric Lambie , Tim Schedl , Meera V Sundaram	2002-03-05	-

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