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171849 pop-1

171849

pop-1

Protein pop-1

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Protein pop-1

研究结论

Date Results Publications
2020-07-11 12:08:00 RNT-1/BRO-1 appears to render POP-1 below the level required for its repressor function, which converts differentiation into self-renewal; conserved Runx/CBFbeta-type stem cell regulators switch asymmetric to proliferative cell division by opposing TCF-related transcriptional repression 31740621
2016-06-04 10:50:00 these results indicate that SYS-1 and POP-1 levels are influenced by the parent cell's SYS-1/POP-1 levels and this may provide an additional mechanism by which POP-1 regulates distinct targets in different developmental contexts. 26488501
2014-12-20 10:45:00 we demonstrate that POP-1 (the C. elegans TCF) also activates target genes through HMG and Helper site interactions. 24516405
2011-11-26 10:35:00 SYS-1 and POP-1 nuclear levels are regulated in opposite directions; the C terminus of POP-1 is essential for LIT-1 phosphorylation and is specifically bound by the diverged beta-catenin WRM-1 21852394
2011-01-01 11:14:00 Animals with reduced function of the Wnt-pathway downstream effector POP-1 have as many as 67 seam cells. The 'Wnt/beta-catenin asymmetry' pathway is required for the proper stem cell-like asymmetric division of seam cells. 20849842

名称对应

Type IDs
Gene
UniProtKB-ID: POP1_CAEEL
UniprotKB: Q10666
UniParc: UPI000237497B
EMBL: U37532, FO081765
EnsemblGenome: WBGene00004077
KO: cel:CELE_W10C8.2
Nucleutide sequences
EMBL-CDS: CCD73394.2, AAC05308.1
Gene_ORFName: W10C8.2
EnsemblGenome_TRS: W10C8.2.1
Protein sequencees
EnsemblGenome_PRO: W10C8.2.1
RefSeq: NP_491053.4
Others
UniRef100: UniRef100_Q10666
UniRef90: UniRef90_Q10666
UniRef50: UniRef50_Q10666
UniGene: Cel.19670

全选

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研究热度

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