| Type | Description |
|---|---|
| Definition | matrilin 3 |
| Date | Results | Publications |
|---|---|---|
| 2016-09-17 12:03:00 | Data show that hand osteoarthritis (HOA)-related matrilin-3 mutation (T298M) leads to a high expression level of growth arrest DNA damage-inducible gene 153 (GADD153) | 26499313 |
| 2015-07-25 11:13:00 | MATN3 plays a regulatory role in cartilage homeostasis due to its capacity to induce IL-1Ra, upregulate gene expression of major cartilage matrix components, and downregulate the expression of OA-associated matrix-degrading proteinases in chondrocytes. | 22967398 |
| 2015-02-14 10:03:00 | MATN3 may have the inherent ability to inhibit premature chondrocyte hypertrophy by suppressing BMP-2/Smad1 activity | 25331953 |
| 2014-08-09 12:27:00 | study will facilitate better awareness of the differential diagnoses that might be associated with the PSACH/MED spectrum and subsequent care of PSACH/MED patients | 24312420 |
| 2012-12-08 11:04:00 | Lack of COMP and matrilin 3 leads to increased deposition of TIMP-3, which causes partial inactivation of matrix metalloproteinases in bone, including MMP-13. | 22378539 |
| Type | IDs |
|---|---|
| Synonymous | AV009181 |
| Gene |
UniProtKB-ID:
MATN3_MOUSE
UniprotKB:
O35701
UniParc:
UPI0000004091
EMBL:
AK048456,
AJ242932,
AJ242929,
AJ242936,
AJ242934,
AJ242931,
AJ242930,
AJ242933,
Y10521,
AJ242935
Ensembl:
ENSMUSG00000020583
KO:
mmu:17182
|
| Nucleutide sequences |
EMBL-CDS:
CAB72265.1,
BAC33343.1,
CAA71532.1
Ensembl_TRS:
ENSMUST00000020899
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000020899
RefSeq:
NP_034900.4
|
| Others |
UniRef100:
UniRef100_O35701
UniRef90:
UniRef90_O35701
UniRef50:
UniRef50_O15232
UniGene:
Mm.42226
CCDS:
CCDS25806.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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