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17174 Masp1

17174

Masp1

mannan-binding lectin serine peptidase 1

protein-coding

Mus musculus

基因描述

Type Description
Definition mannan-binding lectin serine peptidase 1

研究结论

Date Results Publications
2020-05-16 12:34:00 MASP-3 orchestrates the overall complement reaction through the activation of FD. 31399515
2019-08-17 10:58:00 data indicate that MASP-1/3 plays essential roles in the development of lupus-like glomerulonephritis in MRL/lpr mice, most likely via activation of the lectin pathway and/or alternative pathway. 29892304
2018-11-17 12:03:00 It has been shown that key proteins in the lectin arm of this pathway, MASP1, MASP2 and C3, are expressed in the developing cortex and that neuronal migration is impaired in knockout and knockdown mice. 28462915
2017-09-30 10:29:00 MBL-KO (Figure 1a) and MASP-1-KO (Figure 1b) mice are poor mobilizers in response to mobilizing agents compared with WT littermates 27733776
2017-08-19 12:04:00 this study shows that inhibition of MASP-1/3 by gene silencing is sufficient to ameliorate collagen Ab-induced arthritis in mice 27707997

名称对应

Type IDs
Synonymous AW048060, CCPII, Crarf, Masp1/3
Gene
UniProtKB-ID: MASP1_MOUSE, A0A2R8VHR3_MOUSE
UniprotKB: P98064, A0A2R8VHR3
UniParc: UPI00000E92D0, UPI0000F059C5, UPI0001548E2F
EMBL: AB049755, D16492, AC154571, BC131637, CH466521, AY135527, AC163612, AY135525, AK031598, BC131638
Ensembl: ENSMUSG00000022887
KO: mmu:17174
Nucleutide sequences
EMBL-CDS: BAB69688.1, BAA03944.1, EDK97671.1, AAI31639.1, AAN39850.1, EDK97670.1, AAI31638.1, BAC27469.1
Ensembl_TRS: ENSMUST00000229619, ENSMUST00000089883, ENSMUST00000230040
Protein sequencees
Ensembl_PRO: ENSMUSP00000155665, ENSMUSP00000087327, ENSMUSP00000155343
RefSeq: NP_001346012.1, NP_032581.2, XP_036015702.1, XP_036015704.1, XP_006521892.1, XP_036015703.1
Others
UniRef100: UniRef100_P98064, UniRef100_A0A2R8VHR3
UniRef90: UniRef90_Q8CHN8, UniRef90_Q8CHN8-3
UniRef50: UniRef50_P48740, UniRef50_Q8CHN8-3
UniGene: Mm.1213
CCDS: CCDS88904.1, CCDS37303.1

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