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171647 wwp-1

171647

wwp-1

E3 ubiquitin-protein ligase

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition E3 ubiquitin-protein ligase

研究结论

Date Results Publications
2015-08-08 11:22:00 WWP-1 directly interacts with KLF-1 and mediates multiple monoubiquitylation of KLF-1 in vitro and in cellulo. The data support a model in which modulation of KLF-1 by WWP-1 regulates diet-restriction-induced longevity. 24805825
2011-01-15 11:16:00 WWP-1 and DAF-16 function in parallel within the fundamental DAF-2 insulin/IGF-1 signaling network to regulate fundamental cellular responses in C. elegans 20209166
2010-01-21 00:00:00 results indicate that WWP-1 and UBC-18 function to ubiquitinate substrates that regulate diet-restriction-induced longevity 19553937
2010-01-21 00:00:00 WWP-1 is the putative E3 ubiquitin ligase mediating the degradation of the large RNA polymerase II (RNA pol II) subunit, AMA-1 under UV irradiation. 18053776

名称对应

Type IDs
Gene
UniProtKB-ID: V6CLY4_CAEEL, Q95XU3_CAEEL, Q9N2Z7_CAEEL, V6CJJ8_CAEEL
UniprotKB: V6CLY4, Q95XU3, Q9N2Z7, V6CJJ8
UniParc: UPI0003C9A1B2, UPI0003C99FD0, UPI0000083943, UPI0000083942
EMBL: BX284601
EnsemblGenome: WBGene00007009
KO: cel:CELE_Y65B4BR.4
Nucleutide sequences
EMBL-CDS: CDK13616.1, CCD71932.1, CCD71931.1, CDK13617.1
Gene_ORFName: Y65B4BR.4, CELE_Y65B4BR.4, Y65B4BR.4, CELE_Y65B4BR.4, Y65B4BR.4, CELE_Y65B4BR.4, Y65B4BR.4, CELE_Y65B4BR.4
Protein sequencees
RefSeq: NP_001293272.1, NP_740775.1, NP_740776.1, NP_001293271.1
Others
UniRef100: UniRef100_Q95XU3, UniRef100_Q9N2Z7
UniRef90: UniRef90_Q9N2Z7
UniRef50: UniRef50_Q9N2Z7
UniGene: Cel.7528

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