| Type | Description |
|---|---|
| Definition | Dual oxidase 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-16 11:13:00 | hpx-2 mutant animals possessed a weaker cuticle structure, indicated by higher permeability to a DNA dye, but exhibited no obvious morphological defects. In addition, fluorescent labeling of HPX-2 revealed its expression in the pharynx, an organ in which BLI-3 is also present. Interestingly, loss of HPX-2 increased intestinal colonization of E. faecalis, suggesting its role in the pharynx may limit intestinal colonization | 30695063 |
| 2018-02-10 11:42:00 | Here, the authors identified the Caenorhabditis elegans orthologue of mammalian mediator of ErbB2-driven cell motility, MEMO-1, as a protein that inhibits BLI-3/NADPH oxidase. | 28085666 |
| 2017-12-02 12:15:00 | proline catabolism governs reactive oxygen species homeostasis and subsequent activation of SKN-1, a critical transcription factor regulating xenobiotic stress response and pathogen defense. Intriguingly, proline catabolism-mediated activation of SKN-1 requires cell-membrane dual-oxidase Ce-Duox1/BLI-3, highlighting the importance of interaction between mitochondrial and cell-membrane components in host defense. | 27974198 |
| 2015-11-21 10:52:00 | BLI-3/TSP-15/DOXA-1 dual oxidase complex is required for the toxic pleiotropic effects of excess iodide. | 25480962 |
| 2013-01-05 10:55:00 | We demonstrated that TSP-15, BLI-3, and DOXA-1 form complexes in vitro and in vivo. Cell-fusion-based analysis suggested that association with TSP-15 at the cell surface is crucial for BLI-3 activation to release H(2)O(2). | 23028364 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
DUOX1_CAEEL
UniprotKB:
O61213
UniParc:
UPI0000078ED9
EMBL:
BX284601,
AF229855
EnsemblGenome:
WBGene00000253
KO:
cel:CELE_F56C11.1
|
| Nucleutide sequences |
EMBL-CDS:
AAF71303.1,
CCD71714.1
Gene_ORFName:
F56C11.1
EnsemblGenome_TRS:
F56C11.1.1
|
| Protein sequencees |
EnsemblGenome_PRO:
F56C11.1.1
RefSeq:
NP_490686.3
|
| Others |
UniRef100:
UniRef100_O61213
UniRef90:
UniRef90_O61213
UniRef50:
UniRef50_O61213
UniGene:
Cel.31857
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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