| Type | Description |
|---|---|
| Definition | microfibrillar-associated protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:33:00 | Microfibril-Associated Protein 2 (MFAP2) Potentiates Invasion and Migration of Melanoma by EMT and Wnt/beta-Catenin Pathway. | 32464633 |
| 2019-02-16 11:22:00 | Data implicate systemic metabolic dysfunction in the development of bone fragility in germline Mfap2(-/-) mice. Also, MAGP1 protein was detected in the Mfap2(Prx-/-) hematopoietic bone marrow, despite of its absence in osseous bone matrix and its transcript at both sites. This suggests MAGP1 from a secondary site may accumulate in the bone marrow, but not into the bone matrix, during times of regional MAGP1 depletion. | 29519758 |
| 2014-09-20 11:47:00 | Findings indicate that the regulation of TGF-beta by MAGP1 is protective against the effects of metabolic stress, and its absence predisposes individuals to metabolic dysfunction. | 24458361 |
| 2012-06-16 10:41:00 | These studies provide support for increased RANKL expression associated with MAGP1 deficiency and provide a link to altered TGF-beta signaling as a possible causative signaling pathway regulating RANKL expression in MAGP1-deficient osteoblasts. | 21898536 |
| 2010-09-20 11:05:00 | MAGP1 is a regulator of bone remodeling, and its absence results in osteopenia associated with an increase in osteoclast number | 20501659 |
| Type | IDs |
|---|---|
| Synonymous | AI893631, Magp, Magp1 |
| Gene |
UniProtKB-ID:
MFAP2_MOUSE,
Q99PM0_MOUSE
UniprotKB:
P55002,
Q99PM0
UniParc:
UPI0000001AB4,
UPI00000E5C90
EMBL:
AL645625,
L23769,
BC035490,
AK164920,
AK160213,
AF268473
Ensembl:
ENSMUSG00000060572
KO:
mmu:17150
|
| Nucleutide sequences |
EMBL-CDS:
AAH35490.1,
AAA16448.1,
BAE37967.1,
AAG49554.1,
BAE35693.1
Ensembl_TRS:
ENSMUST00000166376,
ENSMUST00000071977
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000132711,
ENSMUSP00000071868
RefSeq:
XP_006538677.1,
NP_032572.3,
NP_001155271.2,
NP_001356221.1,
XP_006538675.1
|
| Others |
UniRef100:
UniRef100_P55002
UniRef90:
UniRef90_P55002
UniRef50:
UniRef50_P27424
UniGene:
Mm.7386
CCDS:
CCDS18860.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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