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17149 Magoh

17149

Magoh

mago homolog, exon junction complex core component

protein-coding

Mus musculus

基因描述

Type Description
Definition mago homolog, exon junction complex core component

研究结论

Date Results Publications
2020-07-11 10:49:00 findings implicate Magoh as a crucial regulator of interneuron development 31857347
2017-05-27 10:25:00 we first show that Eif4a3 haploinsufficiency phenocopies aberrant neurogenesis and microcephaly of Magoh and Rbm8a mutant mice.we show that genetic ablation of one downstream pathway, p53, significantly rescues microcephaly of all 3 EJC mutant 27618312
2014-04-26 11:02:00 findings show 2 genes MAGOH and MAGOHB are expressed in mammals; in macrophages, expression of MAGOHB but not MAGOH mRNA increases after LPS stimulation; both MAGOH proteins interact with other exon junction complex (EJC) components, incorporate into mRNA-bound EJCs and activate nonsense-mediated decay 23917022
2013-04-20 14:03:00 These results point to a central role for Magoh in melanocyte development. 23333945
2011-04-16 11:09:00 mouse magoh is involved in cyclin-dependent kinase regulation. 21210908

名称对应

Type IDs
Synonymous Mago-m, Mos2
Gene
UniProtKB-ID: MGN_MOUSE
UniprotKB: P61327
UniParc: UPI0000022F39
EMBL: AK011512, AF007862, AF035939, BC018176, CH466527, AL611936
Ensembl: ENSMUSG00000028609
KO: mmu:17149
Nucleutide sequences
EMBL-CDS: AAC40044.1, EDL30768.1, AAH18176.1, BAB27668.1, AAB66722.1
Ensembl_TRS: ENSMUST00000030348
Protein sequencees
Ensembl_PRO: ENSMUSP00000030348
RefSeq: NP_001269666.1
Others
UniRef100: UniRef100_P61326
UniRef90: UniRef90_P61326
UniRef50: UniRef50_P61326
UniGene: Mm.808
CCDS: CCDS18441.1

全选

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研究热度

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