| Type | Description |
|---|---|
| Definition | ELOVL fatty acid elongase 6 |
| Date | Results | Publications |
|---|---|---|
| 2017-11-04 12:40:00 | dysregulation of Elovl6-driven long-chain fatty acid metabolism induces phenotypic switching of VSMC via production and AMPK/KLF4 signaling that leads to growth arrest and downregulation of VSMC marker expression. | 27881420 |
| 2011-07-30 10:44:00 | Results show that delta-6 desaturase as well as elongase-6 expressions were upregulated in 3-month-old Zucker fatty rats as compared to lean littermates. | 21172452 |
| 2011-06-04 10:39:00 | Overt type 2 diabetes is associated with diminished islet expression of SCD and Elovl6, and this can disrupt desaturation of saturated FAs to MUFAs, rendering beta-cells more susceptible to saturated FA-induced ER stress and apoptosis. | 21266672 |
| 2011-03-26 12:11:00 | increased expression genes encoding Scd1, Elovl6, and other key lipogenic enzymes may favor fat storage after chronic food restriction/refeeding and may be part of the molecular mechanism by which food restriction/refeeding increases body weight | 20721682 |
| 2010-10-23 11:10:00 | These findings demonstrate that coordinated induction of fatty acid elongases Elovl5 and 6 and desaturase activity is required for balanced synthesis of specific n-7 versus n-9 MUFA species. | 20228221 |
| Type | IDs |
|---|---|
| Synonymous | Lce2, rELO2 |
| Gene |
UniProtKB-ID:
ELOV6_RAT
UniprotKB:
Q920L6
UniParc:
UPI00000E79ED
EMBL:
AB071986
Ensembl:
ENSRNOG00000010468,
ENSRNOG00000048949
KO:
rno:102549542,
rno:171402
|
| Nucleutide sequences |
EMBL-CDS:
BAB69888.1
Ensembl_TRS:
ENSRNOT00000014155,
ENSRNOT00000071270
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000014155,
ENSRNOP00000067070
RefSeq:
XP_017452388.1,
NP_599210.1
|
| Others |
UniRef100:
UniRef100_Q920L6
UniRef90:
UniRef90_Q9H5J4
UniRef50:
UniRef50_Q9H5J4
UniGene:
Rn.46942
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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