| Type | Description |
|---|---|
| Definition | CD40 molecule |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:26:00 | Renal Fibrosis Is Significantly Attenuated Following Targeted Disruption of Cd40 in Experimental Renal Ischemia. | 32200719 |
| 2020-02-29 11:37:00 | CD40 was a direct target of miR-16 and was negatively regulated by miR-16 in H9c2 cells stimulated by LPS. The ablation of CD40 aggravated the biological activities of miR-16 in LPS-induced H9c2 cells. | 31777165 |
| 2018-11-10 10:41:00 | Transient middle cerebral artery occlusion (MCAO) rats yielded an acceleration of thrombus formation that was accompanied by increased CD40 levels in serum. The brain infarction was significantly decreased in CD40 antagonist treatment group compared to MCAO model group. The mTOR/S6K signaling was activated in MACO model than that of CD40 antagonist treatment group. | 29843579 |
| 2017-11-04 13:03:00 | Cd40 plays a crucial role in the development of hypertensive renal disease via development of renal fibrosis. | 27692815 |
| 2017-03-04 11:33:00 | SIRT1 inhibits LPS-induced CD40 expression in renal medullary collecting duct cells by suppressing the TLR4-NF-kappaB signaling pathway | 27916733 |
| Type | IDs |
|---|---|
| Synonymous | Tnfrsf5 |
| Gene |
UniProtKB-ID:
Q4QQW2_RAT
UniprotKB:
Q4QQW2
UniParc:
UPI00005068C6
EMBL:
AABR07054571,
BC097949,
CH474005
Ensembl:
ENSRNOG00000018488
KO:
rno:171369
|
| Nucleutide sequences |
EMBL-CDS:
AAH97949.1,
EDL96468.1
Gene_ORFName:
rCG_32260
Ensembl_TRS:
ENSRNOT00000055148
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000052022
RefSeq:
XP_008760687.1,
NP_599187.1,
XP_006235573.1,
XP_008760686.1,
XP_008760685.1
|
| Others |
UniRef100:
UniRef100_Q4QQW2
UniRef90:
UniRef90_Q4QQW2
UniRef50:
UniRef50_P27512
UniGene:
Rn.25180
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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