| Type | Description |
|---|---|
| Definition | microsomal glutathione S-transferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-02 12:13:00 | The functional unit is a homotrimer centered on the crystallographic three-fold axes of the unit cell. The GSH substrate binds in an extended conformation at the interface between two subunits of the trimer supported by new in vitro mutagenesis data. | 28801553 |
| 2015-01-03 12:48:00 | Since Mgst1expression was reported to decline with age, our results could represent a putative adaptive process during aging. It could also be an early mechanism protecting neuronal cells against some neurodegenerative insults | 24419913 |
| 2012-02-25 10:27:00 | Two doxorubicin derivatives/prodrugs (DNS-DOX; MNS-DOX) are substrates for MGST1; neoplasm drug resistance can be overcome in cell lines over-expressing recombinant MGST1. | 21851097 |
| 2011-12-13 16:00:00 | These results indicate that mitochondrial membrane glutathione transferase in the outer mitochondrial membrane is activated by gallic acid, which may contribute to mitochondrial permeability transition pore formation. | 19111564 |
| 2011-07-23 11:16:00 | Increased expression of miR-34a and miR-93 in rat liver during aging, and their impact on the expression of Mgst1 and Sirt1. | 21216258 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
MGST1_RAT,
B6DYQ4_RAT
UniprotKB:
P08011,
B6DYQ4
UniParc:
UPI000015484E
EMBL:
BC063150,
CH473964,
J03752,
FJ179404
Ensembl:
ENSRNOG00000007743
KO:
rno:171341
|
| Nucleutide sequences |
EMBL-CDS:
AAA41281.1,
AAH63150.1,
ACI32121.1,
EDM01575.1
Gene_ORFName:
rCG_29562
Ensembl_TRS:
ENSRNOT00000010579
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000010579
RefSeq:
NP_599176.1
|
| Others |
UniRef100:
UniRef100_P08011
UniRef90:
UniRef90_P08011
UniRef50:
UniRef50_P08011
UniGene:
Rn.2580
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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