| Type | Description |
|---|---|
| Definition | mucosal vascular addressin cell adhesion molecule 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 12:51:00 | MAdCAM-1-Mediated Intestinal Lymphocyte Homing Is Critical for the Development of Active Experimental Autoimmune Encephalomyelitis. | 31114574 |
| 2020-07-18 11:53:00 | the inactivation of Nkx2-3 permits postnatal seeding, and its blocking effect on SILT maturation prevails at later stage. | 30891037 |
| 2019-08-03 13:14:00 | These findings suggest that interactions between MAdCAM-1 and alpha4beta7 integrin and/or unsulfated sLeX and L-selectin may become a dominant mechanism for inflammatory cell recruitment in the absence of 6-sulfo sLeX and contribute to more severe colitis phenotypes seen in mice deficient in both GlcNAc6ST-1 and GlcNAc6ST-2. | 29350564 |
| 2018-03-24 12:00:00 | Loss of MAdCAM-1 has beneficial effects regarding the development of NASH - manifested by reduced hepatic oxidative stress and decreased inflammation. In contrast, beta7-Integrin-deficiency results in increased steatohepatitis. | 28192190 |
| 2016-12-17 11:56:00 | The results uncovered a previously unknown role of integrin a4b7-MAdCAM-1 interactions as drivers of colitis by directing inflammatory monocytes into the colon. | 26349655 |
| Type | IDs |
|---|---|
| Synonymous | AV211525, MAdCAM-1 |
| Gene |
UniProtKB-ID:
G5E838_MOUSE
UniprotKB:
G5E838
UniParc:
UPI00000218C4
EMBL:
AC132265
Ensembl:
ENSMUSG00000020310
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000020554
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000020554
RefSeq:
NP_001345714.1,
NP_038619.2
|
| Others |
UniRef100:
UniRef100_G5E838
UniRef90:
UniRef90_Q61826
UniRef50:
UniRef50_Q13477
UniGene:
Mm.391556
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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