| Type | Description |
|---|---|
| Definition | EDAR (ectodysplasin-A receptor)-associated death domain |
| Date | Results | Publications |
|---|---|---|
| 2017-07-15 10:33:00 | Mouse models with HED also carry Eda, Edar or Edaradd mutations and have defects that map to the same structures.We report that otitis media, rhinitis and nasopharyngitis occur at high frequency in Eda and Edar mutant mice and explore the pathogenic mechanisms related to glandular function, microbial and immune parameters in these lines | 27378689 |
| 2010-01-21 00:00:00 | level of activation of Edar thus determines cusp number and tooth number during tooth development | 15031115 |
| 2010-01-21 00:00:00 | crinkled binds EDAR through a homotypic death domain interaction and mediates engagement of the NF-kappaB pathway, possibly by recruiting TRAF2 to the receptor-signaling complex. | 11882293 |
| Type | IDs |
|---|---|
| Synonymous | 1810032E07Rik, 5830469M23Rik, A630043P06, cr |
| Gene |
UniProtKB-ID:
Q5D0F1_MOUSE
UniprotKB:
Q5D0F1
UniParc:
UPI000000112D
EMBL:
CT954220,
AK042128,
AK075786,
AY071863,
AK041545,
AC154221,
BC030683
Ensembl:
ENSMUSG00000095105
KO:
mmu:171211
|
| Nucleutide sequences |
EMBL-CDS:
BAC30981.1,
BAC35957.1,
AAH30683.1,
AAL60591.1,
BAC31177.1
Ensembl_TRS:
ENSMUST00000179308
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000136158
RefSeq:
XP_006516627.1,
NP_598398.3
|
| Others |
UniRef100:
UniRef100_Q5D0F1
UniRef90:
UniRef90_Q8VHX2
UniRef50:
UniRef50_Q8VHX2
UniGene:
Mm.159671
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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