| Type | Description |
|---|---|
| Definition | mucolipin 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-12 10:58:00 | Mice lacking both mucolipins 3 and 1, but not either one alone, experienced hearing loss as early as at 1 month of age. | 29453205 |
| 2015-12-19 11:22:00 | lack of both mucolipins 1 and 3 causes an accelerated mucolipidosis IV-type of vacuolation in enterocytes | 25521295 |
| 2015-08-22 10:30:00 | Study shows that, when uropathogenic E. coli infect bladder epithelial cells, they are targeted by autophagy but avoid degradation because of their capacity to neutralize lysosomal pH. This change is detected by TRPML3, TRPML3 activation then spontaneously initiates lysosome exocytosis, resulting in expulsion of exosome-encased bacteria. | 26027738 |
| 2011-07-09 12:18:00 | Trpml3 inactivation does not lead to hearing and vestibular impairment in mice | 21179200 |
| 2011-06-04 11:50:00 | Results describe the expression and subcellular distribution of TRPML3 in the inner ear as well as in other sensory organs. | 21344404 |
| Type | IDs |
|---|---|
| Synonymous | 6720490O21Rik, TRPML3, Va |
| Gene |
UniProtKB-ID:
MCLN3_MOUSE,
Q3KP78_MOUSE
UniprotKB:
Q8R4F0,
Q3KP78
UniParc:
UPI0000028567
EMBL:
AK030819,
AK033008,
AK035029,
AF475086,
AY083531,
BC106856
Ensembl:
ENSMUSG00000036853
KO:
mmu:171166
|
| Nucleutide sequences |
EMBL-CDS:
BAC28916.1,
BAC27146.1,
BAC28123.1,
AAM08924.1,
AAL84623.1,
AAI06857.1
Ensembl_TRS:
ENSMUST00000039450
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000038801
RefSeq:
XP_006501148.1,
NP_598921.1,
XP_006501145.1,
XP_006501147.1,
XP_006501150.1,
XP_006501144.1,
XP_006501149.1,
XP_006501146.1
|
| Others |
UniRef100:
UniRef100_Q8R4F0
UniRef90:
UniRef90_Q8R4F0
UniRef50:
UniRef50_Q8R4F0
UniGene:
Mm.114683
CCDS:
CCDS17900.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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