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171138 Kcne2

171138

Kcne2

potassium voltage-gated channel subfamily E regulatory subunit 2

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition potassium voltage-gated channel subfamily E regulatory subunit 2

研究结论

Date Results Publications
2016-02-06 10:08:00 Endogenous KCNE2 in cardiomyocytes is important in maintaining cardiac electrical stability mainly by regulating Ito and action potential duration. 26297229
2015-01-17 13:16:00 The KCNE2 mutation R27C may induce familial atrial fibrillation partially through enhancing the suppression of Cav1.2 calcium channel. 24681347
2013-08-03 11:29:00 KCNE1 and KCNE2, auxiliary subunits of voltage-gated potassium channels, undergo sequential cleavage mediated by either alpha-secretase and presenilin(PS)/gamma-secretase or BACE1 and PS/gamma-secretase in cells. 23504710
2012-07-07 11:58:00 currents generated by homomeric Kv1.4, Kv3.3, and Kv3.4 channels are all strongly suppressed by the single transmembrane domain ancillary (beta) subunits KCNE1 and KCNE2 21943416
2012-07-07 11:58:00 KCNE1 and KCNE2 suppress currents generated by homomeric Kv1.4, Kv3.3, and Kv3.4 channels 21943417

名称对应

Type IDs
Synonymous Mirp1
Gene
UniProtKB-ID: KCNE2_RAT
UniprotKB: P63161
UniParc: UPI000012F15B
EMBL: AF071003, BC089778
Ensembl: ENSRNOG00000029811
KO: rno:171138
Nucleutide sequences
EMBL-CDS: AAH89778.1, AAD28087.1
Ensembl_TRS: ENSRNOT00000040844
Protein sequencees
Ensembl_PRO: ENSRNOP00000045279
RefSeq: NP_598287.1, XP_006248085.1, XP_008766776.1
Others
UniRef100: UniRef100_P63160
UniRef90: UniRef90_P63160
UniRef50: UniRef50_Q9BDR0
UniGene: Rn.48691

全选

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研究热度

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