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171136 Cblb

171136

Cblb

Cbl proto-oncogene B

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition Cbl proto-oncogene B

研究结论

Date Results Publications
2019-06-08 11:12:00 results suggest that ubiquitin and the E3 ubiquitin ligases c-Cbl and Cbl-b function as neuroimmune modulators in the subacute phase of neuropathic pain after nerve injury. 30021515
2019-03-09 12:30:00 Under microgravity conditions, elevated may be a crucial mechanotransducer in skeletal muscle cells, regulating muscle mass through Cbl-b expression activated by the ERK-Egr signaling pathway. 29513566
2010-09-27 11:38:00 Cbl-b promotes chemotherapy-induced apoptosis in rat basophilic leukemia cells through inhibition of Akt and activation of ERK. 20177738
2010-01-21 00:00:00 we report the positional cloning of Iddm/kdp1 and identify a nonsense mutation in Cblb, a member of the Cbl/Sli family of ubiquitin-protein ligases.Cblb is a major susceptibility gene for rat type 1 diabetes mellitus 12118252
2010-01-21 00:00:00 Results indicate that the Cbl-b-dependent destruction of IRS-1 is a critical dual mediator of both increased protein degradation and reduced protein synthesis observed in unloading-induced muscle atrophy. 19546233

名称对应

Type IDs
Gene
UniProtKB-ID: CBLB_RAT, A0A0G2K8K2_RAT
UniprotKB: Q8K4S7, A0A0G2K8K2
UniParc: UPI00000E7314, UPI0000501146
EMBL: AF199504, AB071283, AABR07034073
Ensembl: ENSRNOG00000001982
KO: rno:171136
Nucleutide sequences
EMBL-CDS: BAC05498.1, AAF13271.1
Ensembl_TRS: ENSRNOT00000077220
Protein sequencees
Ensembl_PRO: ENSRNOP00000074638
RefSeq: XP_006248320.1, XP_006248321.1, XP_006248322.1, NP_598285.1, XP_008766848.1
Others
UniRef100: UniRef100_A0A0G2K8K2, UniRef100_Q8K4S7
UniRef90: UniRef90_Q8K4S7, UniRef90_A0A0G2K8K2
UniRef50: UniRef50_Q13191
UniGene: Rn.21799

全选

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研究热度

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