| Type | Description |
|---|---|
| Definition | rabphilin 3A |
| Date | Results | Publications |
|---|---|---|
| 2018-07-28 11:11:00 | Findings indicate that Rph3A activity is linked to the aberrant synaptic localization of GluN2A-expressing NMDARs characterizing levodopa-induced dyskinesias; suggest that Rph3A/GluN2A complex could represent an innovative therapeutic target for those pathological conditions where NMDAR composition is significantly altered. | 28823933 |
| 2016-05-21 12:34:00 | Rph3A interacts with GluN2A and PSD-95 forming a complex that regulates NMDARs stabilization at postsynaptic membranes. | 26679993 |
| 2010-01-21 00:00:00 | rabphilin, by interacting with alpha-actinin, organizes the cell cytoskeleton to facilitate granule localization within F-actin-rich regions | 16043482 |
| 2010-01-21 00:00:00 | Binding of rabphilin to SNAP-25 regulates exocytosis of synaptic vesicles after the readily releasable pool has either been physiologically exhausted by use-dependent depression, or has been artificially depleted by deletion of synaptobrevin. | 16763567 |
| 2010-01-21 00:00:00 | the rabphilin C2B domain interacts directly with the N-terminus of annexin A4 and mediates the co-complexing of these two proteins which co-localise at the plasma membrane annexin; A4 may play a role in synaptic exocytosis. | 14960300 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
RP3A_RAT,
F1LPB9_RAT
UniprotKB:
P47709,
F1LPB9
UniParc:
UPI0001B799EF,
UPI000013456E
EMBL:
U12571,
AC098508
Ensembl:
ENSRNOG00000001368
KO:
rno:171039
|
| Nucleutide sequences |
EMBL-CDS:
AAA62662.1
Ensembl_TRS:
ENSRNOT00000001844
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000001844
RefSeq:
NP_598202.2,
XP_006249442.1,
XP_006249441.1,
XP_006249443.1
|
| Others |
UniRef100:
UniRef100_P47709,
UniRef100_F1LPB9
UniRef90:
UniRef90_P47709
UniRef50:
UniRef50_P47709
UniGene:
Rn.10976
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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