| Type | Description |
|---|---|
| Definition | zinc finger protein 384 |
| Date | Results | Publications |
|---|---|---|
| 2019-06-08 12:43:00 | A better overview of the incidence of EP300-ZNF384 patients that shows that they have a distinct gene signature with concurrent up-regulation of pathway, reduced expression of B-cell regulators and reduced DNA repair capacity. | 29531323 |
| 2018-01-06 12:47:00 | Ectopic expression of EP300-ZNF384 and CREBBP-ZNF384 fusion altered differentiation of mouse hematopoietic stem and progenitor cells and also potentiated oncogenic transformation in vitro.our results indicate that gene fusion is a common class of genomic abnormalities in childhood ALL and that recurrent translocations involving EP300 and CREBBP may cause epigenetic deregulation with potential for therapeutic targeting. | 27903646 |
| 2017-10-07 12:21:00 | EP300-ZNF384 mediates GATA3 gene expression and may be involved in the acquisition of the HSC gene expression signature and characteristic immunophenotype in B-cell precursor acute lymphoblastic leukemia cells. | 28378055 |
| 2017-07-01 11:21:00 | Our observations indicate that ZNF384-related fusion genes consist of a distinct subgroup of B-cell precursor acute lymphoblastic leukemia with a characteristic immunophenotype, while the clinical features depend on the functional properties of individual fusion partners. | 27634205 |
| 2017-06-24 10:28:00 | the frequency of ZNF384 gene rearrangement in pediatric precursor B cell ALL is approximately 3%. | 27392123 |
| Type | IDs |
|---|---|
| Synonymous | CAGH1, CAGH1A, CIZ, ERDA2, NMP4, NP, TNRC1 |
| Gene |
UniProtKB-ID:
ZN384_HUMAN
UniprotKB:
Q8TF68
UniParc:
UPI000036685E,
UPI00001D3EFA,
UPI00001AE6F8
EMBL:
AB070238,
U80738,
BC053361,
CH471116,
AK095734,
AC125494
Ensembl:
ENSG00000126746
KO:
hsa:171017
|
| Nucleutide sequences |
EMBL-CDS:
AAH53361.1,
EAW88756.1,
BAC04618.1,
BAB85125.1,
AAB91437.1
Ensembl_TRS:
ENST00000319770,
ENST00000361959,
ENST00000355772,
ENST00000396801
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000380019,
ENSP00000354592,
ENSP00000321650,
ENSP00000348018
RefSeq:
NP_001372688.1,
NP_001372669.1,
NP_001372726.1,
NP_001372712.1,
NP_001372714.1,
NP_001372679.1,
XP_006719032.1,
NP_001372681.1,
NP_001129206.1,
NP_597733.2,
NP_001372723.1,
NP_001372716.1,
NP_001372701.1,
NP_001372705.1,
NP_001372730.1,
NP_001372700.1,
NP_001372729.1,
NP_001372728.1,
NP_001372685.1,
NP_001372694.1,
NP_001372715.1,
NP_001035009.1,
NP_001372725.1,
NP_001372691.1,
NP_001372670.1,
NP_001372703.1,
NP_001372674.1,
NP_001372709.1,
NP_001372675.1,
NP_001372706.1,
NP_001372686.1,
NP_001372676.1,
NP_001372673.1,
NP_001372719.1,
NP_001372668.1,
NP_001372692.1,
XP_016874443.1,
NP_001372684.1,
NP_001372708.1,
NP_001372696.1,
NP_001372697.1,
NP_001372682.1,
NP_001372724.1,
XP_011519221.1,
NP_001372718.1,
NP_001372702.1,
NP_001372727.1,
NP_001372690.1,
NP_001372710.1,
NP_001372713.1,
NP_001372699.1,
NP_001372689.1,
NP_001372711.1,
NP_001372672.1,
NP_001372677.1,
NP_001372717.1,
XP_024304642.1,
NP_001372721.1,
NP_001372683.1,
NP_001372693.1,
NP_001372722.1,
NP_001372704.1,
NP_001372680.1,
NP_001372678.1,
NP_001372687.1,
NP_001372707.1,
NP_001372698.1,
XP_011519224.1,
NP_001372671.1,
NP_001372695.1,
XP_011519219.1,
NP_001372720.1
|
| Others |
UniRef100:
UniRef100_Q8TF68
UniRef90:
UniRef90_Q8TF68
UniRef50:
UniRef50_Q9EQJ4
UniGene:
Hs.103315,
Hs.714839
CCDS:
CCDS31732.1,
CCDS8557.1,
CCDS44817.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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