| Type | Description |
|---|---|
| Definition | lymphoblastomic leukemia 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-01 11:31:00 | Scl and Lyl1 share functional roles in platelet production by regulating expression of partner proteins including Gata1. This functional redundancy provides one explanation for the absence of Scl and Lyl1 mutations in inherited thrombocytopenia. | 31300405 |
| 2019-11-02 10:28:00 | NHD13 transgenic mice lacking Lyl1 showed accelerated T-ALL and absence of transformation to AML, associated with a loss of multipotent progenitors in the bone marrow. Thus multiple T cell oncogenes induce thymocyte self-renewal via Lmo2/Lyl1. | 30700838 |
| 2019-02-16 11:40:00 | Lyl1 can maintain primitive erythropoiesis. | 30185409 |
| 2014-06-07 12:11:00 | Loss of Lyl1 is associated with lung endothelial barrier disruption. | 24532287 |
| 2013-11-16 11:51:00 | Lyl1 is critical for all oncogenic functions of Lmo2, including upregulation of a stem cell-like gene signature, aberrant self-renewal of thymocytes, and subsequent generation of T-cell leukemia. | 23926305 |
| Type | IDs |
|---|---|
| Synonymous | Lyl-1, bHLHa18 |
| Gene |
UniProtKB-ID:
LYL1_MOUSE,
A0A571BE88_MOUSE
UniprotKB:
P27792,
A0A571BE88
UniParc:
UPI0000024247,
UPI00001F664F
EMBL:
X55055,
CH466525,
AK076114,
CT010167,
AC145556,
BC005736,
X57687
Ensembl:
ENSMUSG00000034041
KO:
mmu:17095
|
| Nucleutide sequences |
EMBL-CDS:
AAH05736.1,
CAJ18375.1,
CAA38896.1,
EDL10953.1,
BAC36194.1,
CAA40870.1
Ensembl_TRS:
ENSMUST00000037165,
ENSMUST00000238562
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000046010,
ENSMUSP00000158636
RefSeq:
XP_006530808.1,
NP_032561.2,
XP_006530807.1
|
| Others |
UniRef100:
UniRef100_P27792
UniRef90:
UniRef90_P27792
UniRef50:
UniRef50_P12980
UniGene:
Mm.4925
CCDS:
CCDS22476.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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