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170945 Chrna2

170945

Chrna2

cholinergic receptor nicotinic alpha 2 subunit

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition cholinergic receptor nicotinic alpha 2 subunit

研究结论

Date Results Publications
2010-01-21 00:00:00 Similar to other nAChR subunits, alpha2 mRNA expression is transiently upregulated during postnatal development and nAChRs containing alpha2 subunits could regulate GABAergic activity during a critical period of network formation. 17046198
2010-01-21 00:00:00 Results suggest that nicotine alters the normal operation of hippocampal circuits by gating inhibitory circuits through activating a non-desensitizing alpha2 nAChR subtype on a distinct population of interneurons. 19385992
2010-01-21 00:00:00 At least two different affinity sites for acetylcholine. Sensitivity to block of alpha4beta2 channels by dihydro-beta-erythroidine was higher than that for alpha2beta2. Current-voltage for alpha2beta2 more strongly rectified than for alpha4beta2. 15026122

名称对应

Type IDs
Synonymous ACHR
Gene
UniProtKB-ID: ACHA2_RAT
UniprotKB: P12389
UniParc: UPI0000125230
EMBL: M20294, L10077, M20296, M20297, M20293, M20292, M20295, AY574253
Ensembl: ENSRNOG00000017424
KO: rno:170945
Nucleutide sequences
EMBL-CDS: AAB60900.1, AAA40664.1, AAS90349.1
Ensembl_TRS: ENSRNOT00000023475
Protein sequencees
Ensembl_PRO: ENSRNOP00000023475
RefSeq: NP_596911.1
Others
UniRef100: UniRef100_P12389
UniRef90: UniRef90_P12389
UniRef50: UniRef50_P04757
UniGene: Rn.9713

全选

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研究热度

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