| Type | Description |
|---|---|
| Definition | ATP binding cassette subfamily C member 4 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-07 11:36:00 | These data suggest that inhibition of MRP4 significantly alleviates sepsis-induced acute lung injury in rats. | 30995593 |
| 2018-01-27 11:51:00 | Data suggest that MRP4 plays role in pharmacokinetics and pharmacodynamic actions of anti-bacterial ciprofloxacin. In these studies, co-administration of dipyridamole, an inhibitor of MRP4, enhanced AUC/MIC values of ciprofloxacin in both normal and inflamed rats; here, inflammation with E. coli O55-B5 LPS was used as model of inflammation in E. coli infection. | 26458556 |
| 2017-03-25 11:41:00 | The data of this study show increased Abcc1, Abcc2, and Abcc4 mRNA expression at the BBB in response to H/R stress and that Abcc gene expression is regulated by Nrf2 signaling. | 28298215 |
| 2015-10-31 10:25:00 | Multidrug resistance-associated proteins 1, 4, 5, and Oatp1a4 were present at the transcript level, but only Mrp1, 4, and 5 were detected at the protein level. | 26244301 |
| 2013-10-26 11:52:00 | Breast cancer resistance protein, the multidrug resistance protein 4 and P-glycoprotein are not involved in the active secretion of PhIP in the rat distal colon. | 23306951 |
| Type | IDs |
|---|---|
| Synonymous | Mrp4, RGD1565953 |
| Gene |
UniProtKB-ID:
Q6QMG6_RAT
UniprotKB:
Q6QMG6
UniParc:
UPI0000351F51
EMBL:
AY533524
KO:
rno:170924
|
| Nucleutide sequences |
EMBL-CDS:
AAS78928.1
|
| Protein sequencees |
RefSeq:
XP_008769161.1,
NP_596902.1
|
| Others |
UniRef100:
UniRef100_Q6QMG6
UniRef90:
UniRef90_Q6QMG6
UniRef50:
UniRef50_O15439
UniGene:
Rn.13195
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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