| Type | Description |
|---|---|
| Definition | integrin-linked kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 11:39:00 | Accompanied by the TGF-beta1-induced phenotype change in rat kidney epithelial cell line NRK-52E, both mRNA and protein levels of ILK were upregulated. Overexpression of ILK remarkably stimulated the phenotype change in NRK-52E cells. ILK is upregulated during renal fibrosis. ILK participates in the development of renal fibrosis by altering phenotypes of renal tubular epithelial cells via a TGF-beta1/smad pathway. | 30657569 |
| 2020-06-13 11:39:00 | ILK initiates the phenotypic transition of pulmonary artery smooth muscle cells. | 31255599 |
| 2017-06-24 10:58:00 | Investigated the role of ILK in cutaneous wound contraction. We found that ILK was involved in cutaneous wound healing, and ILK and PI3K/AKT inhibitors inhibited wound contraction and re-epithelialization, consequently delaying wound healing in vivo. | 27111285 |
| 2016-09-24 10:53:00 | high extracellular concentration of phosphate induced senescence in cultured smooth muscle through the activation of IGF-1 receptor and ILK overexpression | 26467393 |
| 2016-09-17 12:12:00 | Alpha1beta1 and integrin-linked kinase interact and modulate angiotensin II effects on vascular smooth muscle cell proliferation/migration. | 26520903 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
ILK_RAT
UniprotKB:
Q99J82
UniParc:
UPI0000023621
EMBL:
AF329194,
BC062406
Ensembl:
ENSRNOG00000018993
KO:
rno:170922
|
| Nucleutide sequences |
EMBL-CDS:
AAK12419.1,
AAH62406.1
Ensembl_TRS:
ENSRNOT00000025906
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000025906
RefSeq:
NP_596900.1
|
| Others |
UniRef100:
UniRef100_O55222
UniRef90:
UniRef90_O55222
UniRef50:
UniRef50_O55222
UniGene:
Rn.95042
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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