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170913 Abcb1a

170913

Abcb1a

ATP binding cassette subfamily B member 1A

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition ATP binding cassette subfamily B member 1A

研究结论

Date Results Publications
2018-09-29 10:04:00 Galactosemia caused the osmotic stress in lenses; it also markedly leads to the upregulations of aldose reductase, P-glycoprotein, and Clcn3 in lens epithelial cells, together resulting in obvious osmotic expansion in vitro and in vivo. 29527534
2018-06-09 12:21:00 Abcb1a is critical in maintaining blood-testis barrier integrity, while Abcb1b is crucial for junction reassembly at the blood-testis barrier. 28880272
2016-10-22 12:14:00 The placenta and maternal/fetal intestine, brain, kidneys and liver were sampled and analysed for Abcb1a, Abcb1b and Abcg2 expression. 26727197
2016-10-08 12:44:00 Study demonstrates that P-GP expression and function may be altered in cerebral cortex, hippocampus, liver and kidney of rats under the vitamin A deficiency condition. 26729079
2016-04-02 11:23:00 The data indicate that Pgp and Bcrp do not play significant roles in drug distribution into peripheral nerve tissues in rats, while working in concert to regulate brain penetration. 25539457

名称对应

Type IDs
Synonymous Abcb1, Mdr1a
Gene
UniProtKB-ID: Q9JK64_RAT
UniprotKB: Q9JK64
UniParc: UPI00000E814B
EMBL: AABR07059500, AF257746, CH474013, AABR07072972, AABR07059503, AABR07059502, AC133679, AABR07059501
Ensembl: ENSRNOG00000008012
KO: rno:170913
Nucleutide sequences
EMBL-CDS: AAF69007.1, EDL84318.1
Gene_ORFName: rCG_41085
Ensembl_TRS: ENSRNOT00000011166
Protein sequencees
Ensembl_PRO: ENSRNOP00000011166
RefSeq: XP_006236056.1, NP_596892.1
Others
UniRef100: UniRef100_Q9JK64
UniRef90: UniRef90_P21447
UniRef50: UniRef50_P21447
UniGene: Rn.154810

全选

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研究热度

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