| Type | Description |
|---|---|
| Definition | mitogen activated protein kinase kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-15 11:04:00 | used a constitutively active MEK1 gene (CaMEK) transfection strategy to investigate whether CaMEK provides a protective effect against apoptosis and autophagy induced by hydrogen peroxide (H2O2) in neonatal rat cardiac ventricular cardiomyocytes (NCMs) and the underlying mechanisms | 30876692 |
| 2019-11-02 12:45:00 | Biotin labeling of cell surface proteins from cardiomyocytes overexpressing ADAP1 revealed that it reduces the surface expression of b1-integrin, an effect that is strongly potentiated by Mek1ca overexpression. | 30206251 |
| 2018-06-16 10:44:00 | TSG-6 can inhibit the inflammatory response of transplanted vein grafts in rats and reduce vascular injury by downregulation of P38 and JNK signaling pathway. | 28975447 |
| 2016-03-12 10:14:00 | Formalin injection with and without short-term (<10 min) general isoflurane anesthesia induced the same level of phosphorylated ERK expression in spinal cord. | 26272725 |
| 2014-09-27 10:14:00 | TGF-beta1 and FGF2 induce the epithelial-mesenchymal transition of Hertwig's epithelial root sheath through a MAPK/ERK-dependent signaling pathway. | 24610459 |
| Type | IDs |
|---|---|
| Synonymous | Mek1 |
| Gene |
UniProtKB-ID:
MP2K1_RAT
UniprotKB:
Q01986
UniParc:
UPI0000168279
EMBL:
D14591,
D13341,
Z16415,
X62313,
BC089772
KO:
rno:170851
|
| Nucleutide sequences |
EMBL-CDS:
BAA03441.1,
CAA78905.1,
BAA02603.1,
AAH89772.1,
CAA44192.1
|
| Protein sequencees |
RefSeq:
NP_113831.1,
XP_017450916.1
|
| Others |
UniRef100:
UniRef100_Q01986
UniRef90:
UniRef90_Q01986
UniRef50:
UniRef50_Q02750-2
UniGene:
Rn.5850
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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