| Type | Description |
|---|---|
| Definition | megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human) |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 11:09:00 | MLC1 contributes to restore astrocyte homeostasis after inflammation. | 31209783 |
| 2019-09-28 11:04:00 | we examined the cerebellum of Mlc1-over-expressing mouse and found that the distribution of Bergmann glia was normally compacted along the Purkinje cell layer until postnatal day 10 | 29920672 |
| 2019-08-03 10:18:00 | Disturbed astrocyte regulation of ion and water homeostasis in MLC causes hyperexcitability of neuronal networks and seizures | 29466841 |
| 2018-02-03 10:18:00 | Mlc1 overexpression reduced activity of the astrocytic sodium pump, which may underlie white matter edema followed by myelin membrane splitting | 27748972 |
| 2015-05-30 12:42:00 | we demonstrate an evolutionary conserved role for MLC1 in regulating glial surface levels of GLIALCAM, and this interrelationship explains why patients with mutations in either gene (MLC1 or GLIALCAM) share the same clinical phenotype. | 24824219 |
| Type | IDs |
|---|---|
| Synonymous | AW048630, BB074274, Kiaa0027-hp, LVM, MLC, VL, WKL1 |
| Gene |
UniProtKB-ID:
MLC1_MOUSE
UniprotKB:
Q8VHK5
UniParc:
UPI0000025627
EMBL:
AK030396,
AF449425,
BC024719
Ensembl:
ENSMUSG00000035805
KO:
mmu:170790
|
| Nucleutide sequences |
EMBL-CDS:
AAL66020.1,
AAH24719.1,
BAC26941.1
Ensembl_TRS:
ENSMUST00000042594
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000047667
RefSeq:
NP_573504.1,
NP_001351784.1
|
| Others |
UniRef100:
UniRef100_Q8VHK5
UniRef90:
UniRef90_Q8VHK5
UniRef50:
UniRef50_Q15049
UniGene:
Mm.32780
CCDS:
CCDS37173.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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