Ripply3 - ripply transcriptional repressor 3-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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170765 Ripply3

基因描述

Type	Description
Definition	ripply transcriptional repressor 3

研究结论

Date	Results	Publications
2018-09-15 10:53:00	Ripply3 appears to have been activated to enhance the connection between the extracellular matrix and endodermal epithelial cells, as a mechanism to resist the mechanical stress generated during bending of the epithelial sheets.	29471585
2014-09-20 11:35:00	Insm1 works to promote endocrine cell differentiation in a pathway that involves Neurog3 and Ripply3	25053427
2011-01-29 10:50:00	Ripply3-deficient mice exhibit abnormal development of pharyngeal derivatives, including ectopic formation of the thymus and the parathyroid gland, as well as cardiovascular malformation.	21177346

名称对应

Type	IDs
Synonymous	Dscr6
Gene	UniProtKB-ID: DSCR6_MOUSE UniprotKB: Q924S9 UniParc: UPI0000022056 EMBL: BC060291, AK041355, AK172430, CT573086, AB063284 Ensembl: ENSMUSG00000022941 KO: mmu:170765
Nucleutide sequences	EMBL-CDS: BAE43004.1, AAH60291.1, BAB60891.1, BAC30916.1 Ensembl_TRS: ENSMUST00000023660
Protein sequencees	Ensembl_PRO: ENSMUSP00000023660 RefSeq: NP_573492.2
Others	UniRef100: UniRef100_Q924S9 UniRef90: UniRef90_Q924S9 UniRef50: UniRef50_Q924S9 UniGene: Mm.42604 CCDS: CCDS28347.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
29509905	Dysregulation of TBX1 dosage in the anterior heart field results in congenital heart disease resembling the 22q11.2 duplication syndrome. Hum. Mol. Genet. Erica Hasten , Donna M McDonald-McGinn , Terrence B Crowley , Elaine Zackai , Beverly S Emanuel , Bernice E Morrow , Silvia E Racedo	2018-06-01	-
29471585	Ripply3 is required for the maintenance of epithelial sheets in the morphogenesis of pharyngeal pouches. Dev. Growth Differ. Yoshihiro Tsuchiya , Yusuke Mii , Kazunori Okada , Mikio Furuse , Tadashi Okubo , Shinji Takada	2018-02-01	-
28346476	Reduced dosage of Î²-catenin provides significant rescue of cardiac outflow tract anomalies in a Tbx1 conditional null mouse model of 22q11.2 deletion syndrome. PLoS Genet. Silvia E Racedo , Erica Hasten , Mingyan Lin , Gnanapackiam Sheela Devakanmalai , Tingwei Guo , Ertugrul M Ozbudak , Chen-Leng Cai , Deyou Zheng , Bernice E Morrow	2017-03-01	-
25997579	Pharyngeal arch deficiencies affect taste bud development in the circumvallate papilla with aberrant glossopharyngeal nerve formation. Dev. Dyn. Tadashi Okubo , Shinji Takada	2015-07-01	Krt5, Neurog2, Bdnf, Crabp1, Krt8, Ripply3, Neurod1, Nefm, Pax9, Phox2b, Ret, Stmn2, Shh, Sox2, Tbx1, Uchl1
25053427	Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3. Development Anna B Osipovich , Qiaoming Long , Elisabetta Manduchi , Rama Gangula , Susan B Hipkens , Judsen Schneider , Tadashi Okubo , Christian J Stoeckert , Shinji Takada , Mark A Magnuson	2014-08-01	Amigo2, Celsr3, Pawr, Arx, Neurog3, Runx1t1, Cdh1, Chga, Chgb, Fgf14, Fgf9, Gcg, Ghr, Gjd2, Mnx1, Ins1, Ins2, Isl1, Mafb, Ripply3, Maff, Mafg, Mki67, Myt1l, Neurod1, Nhlh1, Nkx2-2, Nkx6-1, Nnat, Pak3, Pax4, Pax6, Pdx1, Pgf, Lgals3bp, Ppy, Scg3, Slc2a2, Sst, Snap25, Snrk, Stat3, Vdr, Zfp148, Cdc42bpa, Jazf1, Lrp11, Fev, Adgre5, Vat1l, Igfbp7, Mafa, Dbpht2, Insm1, Mapk8ip2, Casz1, Pcgf5, Celf3, Cwc22, Spock2, Hmgn3
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21677750	A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley	2011-06-15	-
21177346	Ripply3, a Tbx1 repressor, is required for development of the pharyngeal apparatus and its derivatives in mice. Development Tadashi Okubo , Akinori Kawamura , Jun Takahashi , Hisato Yagi , Masae Morishima , Rumiko Matsuoka , Shinji Takada	2011-01-01	Etv5, Gcm2, Fgf3, Fgf8, Gbx2, Hand2, Foxn1, Ripply3, Pax1, Pax9, Etv4, Pecam1, Tbx1, Tfap2a, Nkx2-1
19554387	The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex. Cerebellum Karl Schilling , John Oberdick	2009-12-01	Cdh22, Nxph4, Sbk1, Slc6a5, Grm2, Grm3, Grm5, Ogt, Laptm4b, Asic2, Ache, Cygb, Bcan, Cacna2d3, Calb2, Cdh13, Cnr1, Cux1, Ephb2, Gad1, Gad2, Grm1, Grm8, Hcn1, Elavl2, Impact, Kcna2, Kcnab3, Kcnma1, Kit, Lamb1, Lhx9, Stard5, Ripply3, Nefm, Nrxn3, Nsg1, Nsg2, Ntn1, Pam, Pax2, Pcp4, Penk, Pfn2, Prkcd, Cabp7, Ptprk, Pvalb, Resp18, Rora, Sst, Snca, Serpini1, Spock1, Socs2, Kcnk13, Tnr, Trpc3, Slc32a1, Vldlr, Nrsn2, Iqsec1, Slc6a1, Iqsec3, Sema4g, Homer3, Abat, Plch1, Cntn4, Cabp1, Snhg11, Eml5, Zmat4, D830030K20Rik, Lypd6, Arl4c, Hapln4, 2900097C17Rik, Nefh, Shisa6, Vgf, Zwint, Ahi1, Rcan2, Slc12a5, Dusp10, Kcng4, Nos1ap, Rassf8, Galnt14, Tspyl4, Spock3, Whrn, Lrrtm1, Chst1, Nrip3, Trim9, Dtnbp1, Slc24a3
18332117	Activator-to-repressor conversion of T-box transcription factors by the Ripply family of Groucho/TLE-associated mediators. Mol. Cell. Biol. Akinori Kawamura , Sumito Koshida , Shinji Takada	2008-05-01	-

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