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170755 Sgk3

170755

Sgk3

serum/glucocorticoid regulated kinase 3

protein-coding

Mus musculus

基因描述

Type Description
Definition serum/glucocorticoid regulated kinase 3

研究结论

Date Results Publications
2019-12-14 11:45:00 The SGK3-triggered ubiquitin-proteasome degradation of podocalyxin and ezrin in podocytes was associated with the stability of the PC/ezrin complex. 30385740
2019-08-17 10:50:00 Study data from human hepatocellular carcinoma (HCC) liver samples, human HCC cells, and Sgk3 knockout mice model suggest that SGK3 plays a role in transducing helical domain mutant PIK3CA signaling during liver tumor development. 30975125
2018-10-27 10:05:00 Taken together, these data strongly suggest that SGK3 plays a significant role in regulating podocyte function, likely by controlling the expression and activity of GSK3. 28935820
2017-06-03 12:33:00 SGK1 and SGK3 are expressed in multiple microglial cell lines. SGK1 and SGK3 may play an important role in regulating microglial viability and inflammatory responses. 27457803
2016-10-29 11:22:00 SGK3 is a positive regulator of KCNA5, which is at least partially effective by abrogating the effect of Nedd4-2. 26824455

名称对应

Type IDs
Synonymous 2510015P22Rik, A330005P07Rik, Cisk, fy, fz
Gene
UniProtKB-ID: SGK3_MOUSE
UniprotKB: Q9ERE3
UniParc: UPI000002273E
EMBL: AK031328, AK171959, AK151181, AK171120, AK171186, AF312007, AK031133, AK146561, AK030314, AK172323
Ensembl: ENSMUSG00000025915
KO: mmu:170755
Nucleutide sequences
EMBL-CDS: BAE42748.1, BAE42298.1, BAC26895.1, BAC27269.1, AAG34115.1, BAE42945.1, BAC27349.1, BAE30182.1, BAE42262.1, BAE27261.1
Ensembl_TRS: ENSMUST00000171265, ENSMUST00000097826, ENSMUST00000168907, ENSMUST00000166384
Protein sequencees
Ensembl_PRO: ENSMUSP00000126861, ENSMUSP00000095437, ENSMUSP00000130078, ENSMUSP00000127462
RefSeq: NP_573483.1, NP_001032848.1, NP_808215.2
Others
UniRef100: UniRef100_Q9ERE3
UniRef90: UniRef90_Q96BR1
UniRef50: UniRef50_Q96BR1
UniGene: Mm.336410
CCDS: CCDS14816.1

全选

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