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170735 Arr3

170735

Arr3

arrestin 3, retinal

protein-coding

Mus musculus

基因描述

Type Description
Definition arrestin 3, retinal

研究结论

Date Results Publications
2016-06-04 10:39:00 The G-protein coupled receptor, DRD4, requires ARR1 and ARR4 for desensitization and internalization. 26169958
2016-05-14 10:20:00 Data indicate that In arrestin 3 deficient mice, where the alpha2B adrenergic receptor has a stronger binding to spinophilin, the hypertensive response is enhanced. 26244553
2014-02-22 11:46:00 rrestin-3 modulates the activity of ubiquitous JNK1 and JNK2 in non-neuronal cells, impacting the signaling pathway that regulates their proliferation and survival. 24257757
2012-04-28 10:35:00 Arrestin-2 and -3 association with beta(2)-adrenergic receptor (beta2AR) significantly enhanced ERK2 binding, but showed little effect on arrestin interactions with the upstream kinases c-Raf1 and MEK1. 22174878
2010-01-25 11:20:00 of arrestin3 to the beta2-adrenergic receptor orchestrates the sequestration of Gq-coupled receptor-induced ERK to the cytosol through direct binding of ERK to arrestin. 19926878

名称对应

Type IDs
Synonymous Arr4, Car, Carfl, Carr
Gene
UniProtKB-ID: ARRC_MOUSE
UniprotKB: Q9EQP6
UniParc: UPI00000274F0
EMBL: AF156979
Ensembl: ENSMUSG00000060890
KO: mmu:170735
Nucleutide sequences
EMBL-CDS: AAG38954.1
Ensembl_TRS: ENSMUST00000113769
Protein sequencees
Ensembl_PRO: ENSMUSP00000109398
RefSeq: XP_006527926.1, XP_017173891.1, XP_006527933.1, XP_006527929.1, XP_006527934.1, XP_017173888.1, XP_006527925.1, NP_573468.1, XP_006527927.1, XP_006527936.1, XP_006527938.1, XP_006527931.1, XP_006527932.1, XP_017173889.1, XP_006527930.1, XP_006527935.1, XP_017173893.1, XP_017173887.1, XP_006527928.1, XP_017173892.1, XP_017173890.1
Others
UniRef100: UniRef100_Q9EQP6
UniRef90: UniRef90_Q9EQP6
UniRef50: UniRef50_P36575
UniGene: Mm.95518
CCDS: CCDS41075.1

全选

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