| Type | Description |
|---|---|
| Definition | oxidation resistance 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 13:55:00 | Serum secreted miR-137-containing exosomes affects oxidative stress of neurons by regulating OXR1 in Parkinson's disease. | 31301273 |
| 2020-02-22 10:51:00 | this study shows that Oxr1 regulates post-translational modifications of peroxiredoxin 2 in the cerebellum | 30389497 |
| 2019-07-06 10:40:00 | we present a dysregulation of metabolites of glucose metabolism at the pre-symptomatic stage in the Oxr1 knockout cerebellum. We then demonstrate that Oxr1 and Gpi1 physically and functionally interact and that the level of Gpi1 oligomerisation is disrupted when Oxr1 is deleted in vivo. Furthermore, we show that Oxr1 modulates the additional and less well-understood roles of Gpi1 as a cytokine and neuroprotective factor. | 29905912 |
| 2017-12-23 10:32:00 | screening a panel of proteins that regulate mitochondrial morphology in bella GCs revealed de-regulation of phospho-Drp1(Ser616), a key mitochondrial fission regulatory factor. Our data provide new insights into the function of Oxr1, revealing that specific isoforms of this novel antioxidant protein are associated with mitochondria. | 27036366 |
| 2015-07-25 10:08:00 | identify OXR1 as the first neuron-specific antioxidant modulator of pathogenesis and disease progression in SOD1-mediated amyotrophic lateral sclerosis | 25753484 |
| Type | IDs |
|---|---|
| Synonymous | 2210416C20Rik, C7, C7B |
| Gene |
UniProtKB-ID:
OXR1_MOUSE,
B1H3M0_MOUSE,
E9Q0A7_MOUSE
UniprotKB:
Q4KMM3,
B1H3M0,
E9Q0A7
UniParc:
UPI00017AA3AD,
UPI00001E95F4,
UPI00017AA3AE,
UPI000058A7DF,
UPI0000021E82,
UPI0000021E81
EMBL:
AC141481,
AF324899,
AC118590,
BK006239,
BC089183,
BC003927,
AF333985,
AC129212,
BC098491,
AK158703,
AC164633
Ensembl:
ENSMUSG00000022307
KO:
mmu:170719
|
| Nucleutide sequences |
EMBL-CDS:
AAK30368.1,
AAH98491.1,
AAH89183.1,
BAE34619.1,
AAK29400.1,
AAH03927.1,
DAA06145.1
Ensembl_TRS:
ENSMUST00000022918,
ENSMUST00000230203,
ENSMUST00000110297,
ENSMUST00000090095,
ENSMUST00000179393,
ENSMUST00000090096,
ENSMUST00000166917,
ENSMUST00000170127
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000136923,
ENSMUSP00000022918,
ENSMUSP00000155237,
ENSMUSP00000105926,
ENSMUSP00000087554,
ENSMUSP00000087553,
ENSMUSP00000130456,
ENSMUSP00000126266
RefSeq:
NP_001123636.1,
XP_006520589.1,
NP_001345906.1,
NP_001123635.1,
XP_036015102.1,
XP_036015098.1,
NP_001345905.1,
XP_030104222.1,
XP_006520594.1,
NP_001123637.1,
NP_001345907.1,
NP_001123638.1,
XP_036015097.1,
XP_036015099.1,
NP_570955.1,
XP_036015100.1
|
| Others |
UniRef100:
UniRef100_Q4KMM3,
UniRef100_B1H3M0,
UniRef100_E9Q0A7
UniRef90:
UniRef90_Q4KMM3,
UniRef90_Q8N573-4
UniRef50:
UniRef50_Q4KMM3,
UniRef50_Q8N573-4
UniGene:
Mm.254267
CCDS:
CCDS49600.1,
CCDS88760.1,
CCDS49598.1,
CCDS27448.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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